An experience of liver transplantation in Latin America: a medical center in Colombia

https://doi.org/10.25100/cm.v46i1.1400

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Published: Mar 30, 2015
Updated: 2015-03-30
Issue: Vol. 46 No. 1 (2015)
Section Original Articles

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Authors

Oscar Santos - Hepatology and Liver Transplantation Unit, Pablo Tobon Uribe Hospital, Medellin, Colombia. - Gastrohepatology Research Group, University of Antioquia, Medellin, Colombia
Mauricio Londoño Gastrohepatology Research Group, University of Antioquia, Medellin, Colombia
Juan Marin - Hepatology and Liver Transplantation Unit, Pablo Tobon Uribe Hospital, Medellin, Colombia - Gastrohepatology Research Group, University of Antioquia, Medellin, Colombia
Octavio Muñoz - Hepatology and Liver Transplantation Unit, Pablo Tobon Uribe Hospital, Medellin, Colombia - Gastrohepatology Research Group, University of Antioquia, Medellin, Colombia
Alvaro Mena Hepatology and Liver Transplantation Unit, Pablo Tobon Uribe Hospital, Medellin, Colombia
Carlos Guzman Hepatology and Liver Transplantation Unit, Pablo Tobon Uribe Hospital, Medellin, Colombia
Sergio Hoyos - Hepatology and Liver Transplantation Unit, Pablo Tobon Uribe Hospital, Medellin, Colombia - Gastrohepatology Research Group, University of Antioquia, Medellin, Colombia
Juan Restrepo - Hepatology and Liver Transplantation Unit, Pablo Tobon Uribe Hospital, Medellin, Colombia - Gastrohepatology Research Group, University of Antioquia, Medellin, Colombia
Maria Arbelaez Epidemiology Research Group, National Faculty of Public Health, University of Antioquia, Medellin, Colombia
Gonzalo Correa - Hepatology and Liver Transplantation Unit, Pablo Tobon Uribe Hospital, Medellin, Colombia - Gastrohepatology Research Group, University of Antioquia, Medellin, Colombia
Abstract


Objective: Liver transplantation is the treatment of choice for acute and chronic liver failure, for selected cases of tumors, and for conditions resulting from errors in metabolism. This paper reports the experience of a medical center in Latin America.


Methods: Were conducted 305 orthotopic liver transplantations on 284 patients between 2004 and 2010. Of these patients, 241 were adults undergoing their first transplantation.


Results: The average age of patients was 52 years old, and 62% of the individuals were male. The most common indication was alcoholic cirrhosis. The rate of patient survival after 1 and 5 years was 82 and 72% respectively. The rate of liver graft survival after 1 and 5 years was 78 and 68% respectively. The main cause of death was sepsis. Complications in the hepatic artery were documented for 5% of the patients. Additionally, 14.5% of the patients had complications in the biliary tract. Infections were found in 41% of the individuals. Acute rejection was observed in 30% of the subjects, and chronic rejection in 3%.


Conclusion: In conclusion, liver transplantation at our medical center in Colombia offers good mid-term results, with a complication rate similar to that reported by other centers around the world.



Keywords
  • Liver transplantation
  • cirrhosis
  • liver graft
  • rejection
  • immunosuppressive
Author Biographies

Oscar Santos, - Hepatology and Liver Transplantation Unit, Pablo Tobon Uribe Hospital, Medellin, Colombia. - Gastrohepatology Research Group, University of Antioquia, Medellin, Colombia

Internal Medicine, Hepatology and Liver Transplant, Pablo Tobon Uribe Hospital, Gastrohepatology Research Group, University of Antioquia, Medellin, Colombia

Mauricio Londoño, Gastrohepatology Research Group, University of Antioquia, Medellin, Colombia

Gastrohepatology Research Group, University of Antioquia, Medellin, Colombia

Juan Marin, - Hepatology and Liver Transplantation Unit, Pablo Tobon Uribe Hospital, Medellin, Colombia - Gastrohepatology Research Group, University of Antioquia, Medellin, Colombia

Internal Medicine, Hepatology and Liver Transplant, Pablo Tobon Uribe Hospital, Gastrohepatology Research Group, University of Antioquia, Medellin, Colombia

Octavio Muñoz, - Hepatology and Liver Transplantation Unit, Pablo Tobon Uribe Hospital, Medellin, Colombia - Gastrohepatology Research Group, University of Antioquia, Medellin, Colombia

Internal Medicine, Hepatology and Liver Transplant, Pablo Tobon Uribe Hospital, Gastrohepatology Research Group, University of Antioquia, Medellin, Colombia

Alvaro Mena, Hepatology and Liver Transplantation Unit, Pablo Tobon Uribe Hospital, Medellin, Colombia

Liver Transplant, Pablo Tobon Uribe Hospital

Carlos Guzman, Hepatology and Liver Transplantation Unit, Pablo Tobon Uribe Hospital, Medellin, Colombia

Liver Transplant, Pablo Tobon Uribe Hospital

Sergio Hoyos, - Hepatology and Liver Transplantation Unit, Pablo Tobon Uribe Hospital, Medellin, Colombia - Gastrohepatology Research Group, University of Antioquia, Medellin, Colombia

Liver Transplant, Pablo Tobon Uribe Hospital

Juan Restrepo, - Hepatology and Liver Transplantation Unit, Pablo Tobon Uribe Hospital, Medellin, Colombia - Gastrohepatology Research Group, University of Antioquia, Medellin, Colombia

Internal Medicine, Hepatology and Liver Transplant, Pablo Tobon Uribe Hospital, Gastrohepatology Research Group, University of Antioquia, Medellin, Colombia

Maria Arbelaez, Epidemiology Research Group, National Faculty of Public Health, University of Antioquia, Medellin, Colombia

Epidemiology Research Group, National Faculty of Public Health, University of Antioquia, Medellin, Colombia

Gonzalo Correa, - Hepatology and Liver Transplantation Unit, Pablo Tobon Uribe Hospital, Medellin, Colombia - Gastrohepatology Research Group, University of Antioquia, Medellin, Colombia

Internal Medicine, Hepatology and Liver Transplant, Pablo Tobon Uribe Hospital, Gastrohepatology Research Group, University of Antioquia, Medellin, Colombia
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How to Cite
Santos, O., Londoño, M., Marin, J., Muñoz, O., Mena, A., Guzman, C., Hoyos, S., Restrepo, J., Arbelaez, M., & Correa, G. (2015). An experience of liver transplantation in Latin America: a medical center in Colombia. Colombia Medica, 46(1), 8–13. https://doi.org/10.25100/cm.v46i1.1400
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Received 2013-08-10
Accepted 2015-03-19
Published 2015-03-30
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