Calcium oral supplementation in adolescent pregnant women.
Main Article Content
Objective: To determine the effect of oral administration of calcium on plasma and ionized free calcium concentration in healthy adolescent pregnant women.
Methods: In a double blind randomized controlled clinical trial were recruited 48 healthy adolescent pregnant women, 24 (50%) received 600 mg of elemental calcium and 24 (50%) received 600 mg of lactose placebo. At the inclusion time the plasma and intracellular free calcium concentrations were measured by standardized techniques. One month later the plasma and intracellular free calcium concentrations in both groups were measured.
Results: At the inclusion time and one month after treatment both groups were comparable for sociodemographic characteristics and the basal intake of calcium (p=0.92, p=0.62). Calcium supplementation did not modify the concentrations of plasma ionized calcium (1.19+0.04 mmol/l vs. 1.23+0.02 mmol/l, p=0.56) and the free intracellular calcium concentration (mmol/l vs. 89.7 mmol/l, p=0.91); similar effects were observed with the placebo treatment (1.20+0.05 mmol/l vs. 1.19+0.03 mmol/l p=0.86; 116.2 mmol/l vs 137.5 mmol/l, p=0.16, respectively).
Conclusions: Oral administration of 600 mg of elemental calcium in adolescent pregnant women did not induce changes in the plasma and intracellular ionized free calcium concentrations and could explain in part the lack effect of this only supplementation in preeclampsia prevention.
Downloads
- Nora Céspedes, Andrés Vallejo, Myriam Arévalo-Herrera, Sócrates Herrera, Malaria vaccines: high-throughput tools for antigens discovery with potential for their development , Colombia Medica: Vol. 44 No. 2 (2013)
- Jaime Arturo Roa, Carlos A. Echandía, María V. Rodríguez, María I. Lozano, Luis J. Arias, Luz Marina Angel, Alvaro J. Caicedo, Maribel Villalba, Beatriz E. Porras, Jaime Valderrama, Katherine Quevedo, Rastreo de cocaína en orina de recién nacidos hijos de madres consumidoras. , Colombia Medica: Vol. 34 No. 1 (2003)
Similar Articles
- Patricio López Jaramillo, Ronald García, Laura Reyes, Silvia Ruiz, Appropriate prenatal care system: the best way to prevent preeclampsia in Andean countries. , Colombia Medica: Vol. 40 No. 2 (2009)
You may also start an advanced similarity search for this article.
The copy rights of the articles published in Colombia Médica belong to the Universidad del Valle. The contents of the articles that appear in the Journal are exclusively the responsibility of the authors and do not necessarily reflect the opinions of the Editorial Committee of the Journal. It is allowed to reproduce the material published in Colombia Médica without prior authorization for non-commercial use