@article{Zea-Vera_Agudelo-Rojas_2015, title={Disseminated bronchiectasis in an adult with Common Variable Immunodeficiency}, volume={46}, url={https://colombiamedica.univalle.edu.co/index.php/comedica/article/view/1738}, DOI={10.25100/cm.v46i1.1738}, abstractNote={<p id="d7e129" class="first">Primary immunodeficiencies (PID) are traditionally considered childhood diseases; however, adults account for 35% of all patients with PID. Antibody deficiencies, especially Common Variable Immunodeficiency (CVID), which have their peak incidence in adulthood, require a high suspicion index. Even though the estimated frequency of CVID is not high (1:25,000), high rates of under diagnosis and under reporting are very likely. The delay in diagnosis increases the morbidity and mortality; therefore, adult physicians should be able to suspect, identify and initiate management of individuals with PID. Here we report the case of a 37 year-old man presenting to the emergency room with dyspnea, fever and cough; he developed respiratory failure requiring mechanical ventilation. He complained of recurring pneumonia associated with widespread bronchiectasis since he was 18 years old. Serum immunoglobulins quantification showed severe hypogammaglobulinemia (total IgG <140 mg/dL; total IgA, 2.9 mg/dL; and total IgM <5 mg/dL). Treatment with Human Intravenous Immunoglobulin (IVIG) 10% was started, and with antibiotic treatment for severe pneumonia (during 14 days) was also prescribed. His clinical evolution has been favorable after one year follow-up. Common Variable Immunodeficiency (CVID) diagnosis was made.</p><p> </p>}, number={1}, journal={Colombia Medica}, author={Zea-Vera, Andres Felipe and Agudelo-Rojas, Olga Lucia}, year={2015}, month={Mar.}, pages={47–50} }