Skip to main content Skip to main navigation menu Skip to site footer
Page Header Logo
  • ABOUT THE JOURNAL
    • Focus and scope
    • Editorial Management Process
  • EDITORIAL POLICY
    • Ethical Publication Standards
    • Open Access Policy
    • Anti-plagiarism Policy
    • Copyright
    • Policy for Journal Archiving
    • Claim Policy
  • AUTHORS
    • Guidelines to Authors
    • Sending and Receiving Papers
    • Structure and Content of Articles
    • Article Evaluation Process
    • ORCID
    • coi_disclosure Colombia Médica ICMJE
    • Copyright Transfer Statement Colombia Médica
  • PEER REVIEW
    • Peer Review Process
    • Evaluation Forms
  • EDITORIAL TEAM
    • Editorial team
    • Contact
  • ARTICLES
    • Current
    • Archives
  • COLLECTIONS
Search
  • Register
  • Login
  1. Home /
  2. Archives /
  3. Vol 44 No 2 (2013) /
  4. Case Report

Albendazole-induced liver injury: a case report

  • Abstract
  • Keywords
  • References

Abstract

We report a case of a 47-year-old male, who was referred to the clinical hepatology services at Pablo Tobón Uribe Hospital for evaluation of a jaundice syndrome. After undergoing several exams, we diagnosed hepatic hydatidosis and the patient was treated with albendazole; however, after five months of uninterrupted treatment the patient again consulted and his liver test showed marked hepatocellular damage. This time, the patient was diagnosed with drug-induced liver injury due to albendazole, based on information from the clinical record, history of drug consumption, clinical and laboratory tests improved after discontinuing the medication and after discarding other possible causes; this diagnosis was supported by the CIOMS/RUCAM scale, which showed a “likely” correlation between hepatocellular damage and drug toxicity etiology.

 

Authors

  • David Ríos Universidad de Antioquia Grupo de Gastrohepatologia UdeA - HPTU
  • Juan Carlos Restrepo Universidad de Antioquia Grupo de Gastrohepatologia UdeA . HPTU

Downloads

Download data is not yet available.

Keywords

  • Hepatitis
  • albendazole
  • drug-induced liver injury (DILI)

References

Vuitton DA. The WHO Informal Working Group on Echinococcosis. Coordinating Board of the WHO-IWGE. Parassitol. 1997; 39(4): 349-53.

Garcia HH, Evans CA, Nash TE, Takayanagui OM, White AC Jr, Botero D, et al. Current consensus guidelines for treatment of neurocysticercosis. Clin Microbiol Rev. 2002; 15(4): 747-56.

Horton J. Albendazole: a review of anthelmintic efficacy and safety in humans. Parasitol. 2000; 121(Suppl 1): 113-32.

Singthong S, Intapan PM, Wongsaroji T, Maleewong W. Randomized comparative trial of two high-dose Albendazole regimens for uncomplicated human strongyloidiasis. Southeast Asian J Trop Med Public Health. 2006; 37(Suppl 3): 32-4.

Brunton L, Lazo JS, Parker KL. Goodman Gilman’s the pharmacological basis of therapeutics. 11th ed. New York: McGraw-Hill; 2006.

Maartens G, Sinxadi P, Pharmacology of anthelmintics: Albendazole, Mebendazole and praziquantel. CME. 2009; 274-6.

Horton J. Albendazole: a broad spectrum anthelminthic for treatment of individuals and populations. Curr Opin Infect Dis. 2002; 15: 599-608.

Choi GY, Yang HW, Cho SH, Kang DW, Go H, Lee WC, et al. Acute drug-induced hepatitis caused by albendazole. J Korean Med Sci Korea South. 2008; 23(5): 903-5.

Amoruso C, Fuoti M, Miceli V, Zito E, Celano MR, De Giorgi A, et al. Acute hepatitis as a side effect of albendazole: a pediatric case. Pediatr Med Chir. 2009; 31(6): 262-4.

Benichou C. Criteria of drug-induced liver disorders. Report of an international consensus meeting. J Hepatol. 1990; 11(2): 272-6.

Lucena MI, Camargo R, Andrade RJ, Perez-Sanchez CJ, Sanches de la Cuesta F. Comparison of two clinical scales for causality assessment in hepatotoxicity. Hepatol. 2001; 33: 123-30.

Ghabril M, Chalasani N, Bjornsson E. Drug-induced liver injury: a clinical update. Curr Opin Gastroenterol. 2010; 26(3): 222-6.

Gil GL, Rodríguez CF, Prieto J, Sánchez RJ, Brasa C, Aguilar L, et al. Randomized controlled trial of efficacy of albendazole in intra-abdominal hydatid disease. Lancet. 1993; 342: 1269-72.

Hussain S, Malik A, Khaja AR, Dass T, Naikoo Z. Role of Albendazole in the management of hydatid cyst liver. Saudi J Gastroenterol. 2011; 17(5): 343-7.

Bildik N, Cevik A, Altintaş M, Ekinci H, Canberk M, Gülmen M. Efficacy of preoperative Albendazole use according to months in hydatid cyst of the liver. J Clin Gastroenterol. 2007; 41(3): 312-6.

  • PDF
  • HTML
  • daguilar, Comite de ética.doc
  • daguilar, DERECHOS DE AUTOR Y AUTORIZACIÓN PUBLICACIÓN.jpg
  • daguilar, c1.jpg
  • daguilar, Downloads.rar
  • daguilar, Comite de ética.doc
  • daguilar, DERECHOS DE AUTOR Y AUTORIZACIÓN PUBLICACIÓN.jpg
  • daguilar, c1.jpg
  • daguilar, Downloads.rar
Published
2013-05-31
Submitted
2012-02-01
| 716 |
How to Cite
Ríos, D., & Restrepo, J. (2013). Albendazole-induced liver injury: a case report. Colombia Médica, 44(2), 118-120. https://doi.org/10.25100/cm.v44i2.1021
  • ACM
  • ACS
  • APA
  • ABNT
  • Chicago
  • Harvard
  • IEEE
  • MLA
  • Turabian
  • Vancouver
Download Citation
  • Endnote/Zotero/Mendeley (RIS)
  • BibTeX
Issue
Vol 44 No 2 (2013)
Section
Case Report

The copy rights of the articles published in Colombia Médica belong to the Universidad del Valle. The contents of the articles that appear in the Journal are exclusively the responsibility of the authors and do not necessarily reflect the opinions of the Editorial Committee of the Journal. It is allowed to reproduce the material published in Colombia Médica without prior authorization for non-commercial use

Online ISSN: 1657-9534
Make a Submission

Bibliographics database

Full-text database

Citation Index

Bibliographical information system

Memberships

Licencia Creative Commons
This work is under License Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) .

Indexed

.
0.82
2018CiteScore
 
 
68th percentile
Powered by  Scopus
.
Information
  • For Authors
Universidad del Valle
Universidad del Valle
  • Cali - Colombia
  • © 1994 - 2020
Dirección:
  • Ciudad Universitaria Meléndez
  • Calle 13 # 100-00
  •  
  • Sede San Fernando
  • Calle 4B N° 36-00
PBX:
  • +57 2 3212100
  • Línea gratuita: 018000 22 00 21
  • A.A.25360
Redes Sociales:

2020 Universidad del Valle - Vigilada MinEducación

//Go to www.addthis.com/dashboard to customize your tools