Skip to main content Skip to main navigation menu Skip to site footer
Page Header Logo
  • ABOUT THE JOURNAL
    • Focus and scope
    • Editorial Management Process
  • EDITORIAL POLICY
    • Ethical Publication Standards
    • Open Access Policy
    • Anti-plagiarism Policy
    • Copyright
    • Policy for Journal Archiving
    • Claim Policy
  • AUTHORS
    • Guidelines to Authors
    • Sending and Receiving Papers
    • Structure and Content of Articles
    • Article Evaluation Process
    • ORCID
    • coi_disclosure Colombia Médica ICMJE
    • Copyright Transfer Statement Colombia Médica
  • PEER REVIEW
    • Peer Review Process
    • Evaluation Forms
  • EDITORIAL TEAM
    • Editorial team
    • Contact
  • ARTICLES
    • Current
    • Archives
  • COLLECTIONS
Search
  • Register
  • Login
  1. Home /
  2. Archives /
  3. Vol 48 No 4 (2017) /
  4. Case Report

Treatment of endo-periodontal lesion using leukocyte- platelet- rich fibrin. A case report

  • Abstract
  • Keywords
  • Author Biographies
  • References

Abstract

Case Description: The main objective of this paper was to report the clinical effectiveness of leukocyte- platelet- rich fibrin (L-PRF) in the treatment of a combined endo-periodontal lesion of an upper first premolar.

Clinical Findings: The tooth had a profound abfraction on the vestibular aspect and presented no mobility but revealed a deep pocket measuring of 11 mm on the mesial vestibular aspect and 14 mm on the mesial palatine aspect. The three dimensional image analysis showed total bone loss in the mesial aspect and an extensively bone loss of the vestibular aspect of the vestibular root.

Treatment and Outcome: Endodontic treatment was performed and periodontal access surgery (surgical periodontal therapy) was done with the application of autologous L-PRF. Three month and 6 months after surgery, the cone beam computed tomography (CBCT) exams showed no bone regeneration in any aspect of the tooth. However, periodontal examination showed a significative improvement in the deepness of surcus. The mesial vestibular aspect had a deep pocket of 3 mm and 5 mm on the mesial palatine aspect showing a reduction in deepness of 8 mm and 9 mm, respectively.Clinical Relevance:  The actual treatment for teeth with bad prognosis is the extraction and replacement with implants. Even though implants are capable of restore function and aesthetic, the abuse of this approach have led to the loss of teeth that could be successfully treated with a less invasive technique. The prognosis of teeth with endoperiodontal lesion is poor but could be enhanced with regenerative therapies. Until now there are no clinical trials and just four case report about the treatment of these teeth with platelet rich fibrin.

Authors

  • Pablo Betancourt Research Centre in Dental Sciences (CICO), Dental School, Universidad de La Frontera, Temuco, Chile
  • Ricardo Elgueta Facultad de Odontología, Universidad de La Frontera, Temuco, Chile
  • Ramon Fuentes Research Centre in Dental Sciences (CICO), Dental School, Universidad de La Frontera, Temuco, Chile

Downloads

Download data is not yet available.

Keywords

  • Blood platelets
  • leukocytes
  • fibrin
  • surgical procedures
  • endodontics

Author Biographies


, Research Centre in Dental Sciences (CICO), Dental School, Universidad de La Frontera, Temuco, Chile

Research Centre in Dental Sciences (CICO), Dental School, Universidad de La Frontera, Temuco, Chile


, Facultad de Odontología, Universidad de La Frontera, Temuco, Chile
Facultad de Odontología, Universidad de La Frontera, Temuco, Chile

, Research Centre in Dental Sciences (CICO), Dental School, Universidad de La Frontera, Temuco, Chile
Research Centre in Dental Sciences (CICO), Dental School, Universidad de La Frontera, Temuco, Chile

References

Rotstein I, Simon JH. Diagnosis, prognosis and decision-making in the treatment of combined periodontal-endodontic lesions. Periodontol 2000. 2004; 34: 165-203.

Sunitha VR, Emmadi P, Namasivayam A, Thyegarajan R, Rajaraman V. The periodontal - endodontic continuum: A review. J Conserv Dent. 2008; 11(2): 54-62.

Anand V, Govila V, Gulati M. Endo-Perio Lesion: Part II (The Treatment) - A Review. Archdent. 2012; 3(1): 10-16.

Goyal L. Clinical effectiveness of combining platelet rich fibrin with alloplastic bone substitute for the management of combined endodontic periodontal lesion. Restor Dent Endod. 2014; 39(1): 51-5.

Bielecki T, Dohan Ehrenfest DM, Everts PA, Wiczkowski A. The role of leukocytes from L-PRP/L-PRF in wound healing and immune defense: new perspectives. Curr Pharm Biotechnol. 2012;13(7): 1153-62.

Mosesson MW, Siebenlist KR, Meh DA. The structure and biological features of fibrinogen and fibrin. Ann N Y Acad Sci. 2001; 936: 11-30.

van Hinsbergh VW, Collen A, Koolwijk P. Role of fibrin matrix in angiogenesis. Ann N Y Acad Sci. 2001; 936: 426-37.

Sharma A, Pradeep AR. Treatment of 3-wall intrabony defects in patients with chronic periodontitis with autologous platelet-rich fibrin: a randomized controlled clinical trial. J Periodontol. 2011; 82(12): 1705-12.

Choukroun J, Adda F, Schoeffler C, Vervelle A. Une opportunité en paro-implantologie: Le PRF.Implantodontie. 2001; 42: 55-62.

Dohan Ehrenfest DM, Rasmusson L, Albrektsson T. Classification of platelet concentrates: from pure platelet-rich plasma (P-PRP) to leucocyte- and platelet-rich fibrin (L-PRF). Trends Biotechnol. 2009; 27(3): 158-67.

Dohan Ehrenfest DM, Del Corso M, Diss A, Mouhyi J, Charrier JB. Three-Dimensional Architecture and Cell Composition of a Choukroun's Platelet-Rich Fibrin Clot and Membrane. J. Periodontol. 2010; 81(4): 546-55.

He L, Lin Y, Hu X, Zhang Y, Wu H. A comparative study of platelet-rich fibrin (PRF) and platelet-rich plasma (PRP) on the effect of proliferation and differentiation of rat osteoblasts in vitro. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009; 108(5): 707-13.

Li Q, Pan S, Dangaria SJ, Kolokythas A, Chu S, Geng Y, et al. Platelet-Rich Fibrin Promotes Periodontal Regeneration and Enhances Alveolar Bone Augmentation. Biomed Res Int. 2013; 2013: 638043. doi:10.1155/2013/638043.

Clipet F, Tricot S, Alno N, Massot M, Solhi H, Cathelineau G, Perez F, De Mello G, Pellen-Mussi P. In vitro effects of Choukroun's platelet-rich fibrin conditioned medium on 3 different cell lines implicated in dental implantology. Implant Dent. 2012; 21(1): 51-6.

El-Sharkawy H, Kantarci A, Deady J, Hasturk H, Liu H, Alshahat M, Van Dyke TE. Platelet-rich plasma: growth factors and pro- and anti-inflammatory properties. J Periodontol. 2007; 78(4): 661-669.

Moojen DJ, Everts PA, Schure RM, Overdevest EP, van Zundert A, Knape JT, Castelein RM, Creemers LB, Dhert WJ. Antimicrobial activity of platelet-leukocyte gel against Staphylococcus aureus. J Orthop Res. 2008; 26(3): 404-10.

Jia WT, Zhang CQ, Wang JQ, Feng Y, Ai ZS. The prophylactic effects of platelet-leucocyte gel in osteomyelitis: an experimental study in a rabbit model. J Bone Joint Surg Br. 2010; 92(2): 304-31

Karunakar P, Prasanna JS, Jayadev M, Shravani GS. Platelet-rich fibrin, a “faster healing aid” in the treatment of combined lesions: A report of two cases. J Indian Soc Periodontol. 2014; 18(5): 651-5.

Singh S. Management of an endo perio lesion in a maxillary canine using platelet-rich plasma concentrate and an alloplastic bone substitute. J Indian Soc Periodontol. 2009; 13(2): 97-100.

Nagaveni NB, Kumari KN, Poornima P, Reddy V. Management of an endo-perio lesion in an immature tooth using autologous platelet-rich fibrin: a case report. J Indian Soc Pedod Prev Dent. 2015; 33(1): 69-73.

Varughese V, Mahendra J, Thomas AR, Ambalavanan N. Resection and Regeneration - A Novel Approach in Treating a Perio-endo Lesion. J Clin Diagn Res. 2015; 9(3): ZD08-10..

  • PDF
  • PDF (Español (España))
  • Full Text
  • HTML (Español (España))
Published
2017-12-22
Submitted
2015-10-28
| 1172 |
How to Cite
Betancourt, P., Elgueta, R., & Fuentes, R. (2017). Treatment of endo-periodontal lesion using leukocyte- platelet- rich fibrin. A case report. Colombia Médica, 48(4), 204-207. https://doi.org/10.25100/cm.v48i4.2140
  • ACM
  • ACS
  • APA
  • ABNT
  • Chicago
  • Harvard
  • IEEE
  • MLA
  • Turabian
  • Vancouver
Download Citation
  • Endnote/Zotero/Mendeley (RIS)
  • BibTeX
Issue
Vol 48 No 4 (2017)
Section
Case Report

The copy rights of the articles published in Colombia Médica belong to the Universidad del Valle. The contents of the articles that appear in the Journal are exclusively the responsibility of the authors and do not necessarily reflect the opinions of the Editorial Committee of the Journal. It is allowed to reproduce the material published in Colombia Médica without prior authorization for non-commercial use

Online ISSN: 1657-9534
Make a Submission

Bibliographics database

Full-text database

Citation Index

Bibliographical information system

Memberships

Licencia Creative Commons
This work is under License Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) .

Indexed

.
0.82
2018CiteScore
 
 
68th percentile
Powered by  Scopus
.
Information
  • For Authors
Universidad del Valle
Universidad del Valle
  • Cali - Colombia
  • © 1994 - 2020
Dirección:
  • Ciudad Universitaria Meléndez
  • Calle 13 # 100-00
  •  
  • Sede San Fernando
  • Calle 4B N° 36-00
PBX:
  • +57 2 3212100
  • Línea gratuita: 018000 22 00 21
  • A.A.25360
Redes Sociales:

2020 Universidad del Valle - Vigilada MinEducación

//Go to www.addthis.com/dashboard to customize your tools