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  1. Home /
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  3. Vol 46 No 4 (2015) /
  4. Editorial

Primary prevention of preeclampsia: myth or reality?

  • Abstract
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Abstract

Preeclampsia is a disease of the human species, described more than a century ago, of unknown cause, which shares with atherosclerosis risk factors, biochemical abnormalities, endothelial dysfunction and a multifactorial origin. Reducing atherosclerosis lethality is achieved with secondary prevention; and similarly, in preeclampsia, early diagnosis and timely obstetric resolution (secondary prevention) prevents that the mother reaches the end of its natural history, where acute overlay of atherosclerotic plaques in the arteries spiral induces multiple organ failure and increases the maternal risk of death1. The hospital care scheme implemented in Colombia achieved a reduction in maternal mortality by 9%, and when complemented with a preventive prenatal outpatient scheme (Biopsychosocial Model) designed to prevent progression of endothelial dysfunction, the reduction of maternal mortality increased up to 25%...............

Authors

  • Julian Alberto Herrera Professor Emeritus of Medicine. Universidad del Valle, Cali, Colombia

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References

Redman C. The six stages of preeclampsia. Pregnancy Hypertens. 2014;4(3):246–246.

Herrera JA, Herrera-Medina R, Herrera-Escobar JP, Nieto-Diaz A. Reduction of maternal mortality due to preeclampsia in Colombia-an interrupted time-series analysis. Colomb Med (Cali) 2014;45(1):25–31.

Hofmeyr GJ, Belizan JM, Von Dadelszen P, Calcium and Pre-eclampsia Study Group Low-dose calcium supplementation for preventing pre-eclampsia: a systematic review and commentary. BJOG. 2014;121(8):951–957.

Campos A. The rol of aspirin in preeclampsia prevention: State of the Art. Acta Med Port. 2015;28(4):517–524. [PubMed]

Campos Mondragón MG, Oliart Ros RM, Martínez Martinez A, Méndez Machado GF, , Angulo Guerrero JO. Metabolic syndrome reversion by polyinsaturated fatty acids ingestión. Med Clin (Barc) 2013;141(12):513–518.

Herrera JA, Arevalo-Herrera M, Shahabuddin AKM, Ersheng G, Herrera S, et al. Calcium and conjugated linoleic acid reduces pregnancy-induced hypertension and decreases intracellular calcium in lymphocytes. Am J Hypertens. 2006;19:381–387.

Alzate A, Herrera-Medina R, Pineda LM. Preeclampsia prevention: a case-control study nested in the cohort. Colomb Med (Cali). 2015; 46(4):156-161.

Herrera JA, Chaudhuri G, López-Jaramillo P. Is infection a major risk to preeclampsia. Med Hypotheses. 2001;57(3):393–397.

Schwartz A. Maternal Mortality. Risk factors, Anthropological Perspectives, Prevalence in Developing Countries and Preventive Strategies for Pregnancy-Related Deaths. New York: Nova Science Publishers Inc; 2015.

Herrera JA, Arévalo-Herrera M, Villegas A, Herrera S, Villalba M, Bromet A. Suplementación oral de calcio en adolescentes embarazadas de bajo nivel socioeconómico y su efecto en las concentraciones de calcio libre intracelular. Colombia Med. 2006;37(S1):9–15.

Henriksen T, Clausen T. The fetal origins hypothesis: placental insufficiency and inheritance versus maternal malnutrition in well-nourished populations. Acta Obstet Gynecol Scand. 2002;81(2):112–114.

Palltto EK, Kilbride HW. Perinatal outcome and later implications of intrauterine growth restriction. Clin Obstet Gynecol. 2006;49(2):257–269.

Ukleba KO, Pavlenishvili IV, Zurabashvili DZ. The influence of perinatal hypoxic-ischemic disorders of central nervous system on adolescent academic achievements and behavioural deviations. Georgian Med News. 2013;218:58–62.

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Published
2015-12-30
Submitted
2015-12-07
| 605 |
How to Cite
Herrera, J. (2015). Primary prevention of preeclampsia: myth or reality?. Colombia Médica, 46(4), 154-155. https://doi.org/10.25100/cm.v46i4.2170
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Vol 46 No 4 (2015)
Section
Editorial

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