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  1. Home /
  2. Archives /
  3. Vol 51 No 2 (2020): Coronavirus disease 2019 /
  4. Reviews

SARS-CoV-2 diagnostic testing alternatives for Latin America

  • Abstract
  • Keywords
  • Author Biography
  • References

Abstract

In the past four months SARS-CoV-2 has reached most countries in the world. Public health strategies based on widespread testing and proper isolation of positive cases have shown to be helpful to reduce local transmission of SARS-CoV-2. Confirmatory tests, that identify viral RNA, and screening serological tests that identify viral antigens or host antibodies against viral proteins are part of the tools that nations can use to fight infectious disease epidemics. Understanding how each test works can provide insights about their test characteristics and how they can be used for different clinical and public health goals. Testing is a key strategy to reduce viral transmission, not only for this epidemic, but also for others to come.

 

Authors

  • Julián Santaella-Tenorio Universidad del Valle. Cali, Colombia https://orcid.org/0000-0003-3060-5994

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Keywords

  • SARS-CoV-2
  • diagnostic
  • covid-19
  • Severe Acute Respiratory Syndrome
  • SARS Virus
  • Virus RNA
  • Coronavirus
  • Quarantine
  • RNA-Directed DNA Polymerase
  • Viral Proteins
  • Nucleocapsid
  • Antibodies, Monoclonal
  • Point-of-Care Systems
  • Pandemics
  • Indicators and Reagents
  • Immobilized Proteins

Author Biography


, Universidad del Valle. Cali, Colombia

Julian_Santaella_copy11.jpg

Veterinary doctor with master's and doctorate studies in epidemiology. Julian has worked in research on transmission of infectious agents from animals to humans. In the last 10 years, he has investigated the prevention of violence and injuries, mental health and the consumption of psychoactive substances in the population. He is currently a professor and coordinator of the Master of Clinical Epidemiology at the Universidad Javeriana, professor at the School of Public Health at the Universidad del Valle and consultant to the Center for Opioid Epidemiology and Policy at NYU Langone 

AAA_orcid_id69.png https://orcid.org/0000-0003-3060-5994

References

World Health Organization. Coronavirus disease (COVID-19) technical guidance: Laboratory testing for 2019-nCoV in humans. Available from: https://www.who.int/emergencies/diseases/novel-coronavirus-2019/technical-guidance/laboratory-guidance. 2020. Accessed April 6, 2020.

NUS Saw Swee Hock School of Public Health. COVID-19 Science Report: Diagnostics. 2020. Doi: 10.25540/e3y2-aqye. Available from: https://sph.nus.edu.sg/wp-content/uploads/2020/03/COVID-19-Science-Report-Diagnostics-30-Mar.pdf Accessed April 6, 2020.

Bai Y, Yao L, Wei T, Tian F, Jin DY, Chen L, et al. Presumed Asymptomatic Carrier Transmission of COVID-19. JAMA. 2020;323(14):1406-1407. https://doi.org/10.1001/jama.2020.2565

Huang P, Liu T, Huang L, Liu H, Lei M, Xu W, et al. Use of Chest CT in Combination with Negative RT-PCR Assay for the 2019 Novel Coronavirus but High Clinical Suspicion. Radiology. 2020;295(1):22-23. https://doi.org/10.1148/radiol.2020200330

Xie X, Zhong Z, Zhao W, Zheng C, Wang F, Liu J. Chest CT for Typical 2019-nCoV Pneumonia: Relationship to Negative RT-PCR Testing. Radiology. 2020:200343. https://doi.org/10.1148/radiol.2020200343

Foundation for Innovative New Diagnostics (FIND). SARS-COV-2 diagnostic pipeline. 2020. Available from: https://www.finddx.org/covid-19/pipeline/. Accessed April 06, 2020.

Cheng MP, Papenburg J, Desjardins M, Kanjilal S, Quach C, Libman M, et al. Diagnostic Testing for Severe Acute Respiratory Syndrome-Related Coronavirus-2: A Narrative Review. Ann Intern Med. 2020; https://doi.org/10.7326/M20-1301

Kelly-Cirino C, Mazzola LT, Chua A, Oxenford CJ, Van Kerkhove MD. An updated roadmap for MERS-CoV research and product development: focus on diagnostics. BMJ Glob Health. 2019;4(Suppl 2):e001105. https://doi.org/10.1136/bmjgh-2018-001105

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Abbott press releases. Abbott launches molecular point-of-care test to detect novel coronavirus in as little as five minutes. Available from: https://abbott.mediaroom.com/2020-03-27-Abbott-Launches-Molecular-Point-of- Care-Test-to-Detect-Novel-Coronavirus-in-as-Little-as-Five-Minutes. 2020. Accessed April 06, 2020.

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Published
2020-05-14
Submitted
2020-04-08
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How to Cite
Santaella-Tenorio, J. (2020). SARS-CoV-2 diagnostic testing alternatives for Latin America. Colombia Médica, 51(2), e-4272. https://doi.org/10.25100/cm.v51i2.4272
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Vol 51 No 2 (2020): Coronavirus disease 2019
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Reviews

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