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  1. Home /
  2. Archives /
  3. Vol 51 No 2 (2020): Coronavirus disease 2019 /
  4. Reviews

Drug Repositioning for COVID-19

  • Abstract
  • Keywords
  • Author Biography
  • References

Abstract

Drug repositioning is a strategy that identifies new uses of approved drugs, to treat conditions different from their original purpose. With the advance of COVID-19 and the declaration of a pandemic; It has become the closest alternative to slow the advance of the virus. Antimalarial, antiviral drugs, antibiotics, glucocorticoids, monoclonal antibodies, among others, are being studied; his findings, although preliminary, could establish a starting point in the search for a solution.

In this article, we present a selection of drugs, of different classes and with potential activity to combat COVID-19, whose trials are ongoing; and as proofs of concept, double blind, event-driven add-on, would allow proposing research that generates results in less time and preserving the quality criteria for drug development and approval by regulatory agencies.

Authors

  • Vicente Benavides-Cordoba Universidad del Valle. Cali, Colombia https://orcid.org/0000-0002-9129-0183

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Keywords

  • COVID-19
  • drug repositioning
  • pandemic
  • therapeutic alternatives

Author Biography


, Universidad del Valle. Cali, Colombia

Foto.jpg

Education:
Physiotherapist / Universidad del Cauca
Specialist in Cardiopulmonary Physical Therapy / Universidad del Valle
PhD (c) in Biomedical Sciences / Universidad del Valle
Clinical Training Fellowship / European Respiratory Society - Amsterdam Medical Center

Research Area
Pulmonary Rehabilitation, Pulmonary Hypertension, Drug Repositioning.

orcid_id43.png https://orcid.org/0000-0002-9129-0183

Recent Articles

Benavides-Cordoba, V., Silva-Medina, M., Varela, M. X., & Palacios, M. (2020). Subchronic
toxicity of the pulmonary hypertension model due to low-dose monocrotaline in rats. Journal of
Pharmacy & Pharmacognosy Research, 8(4), 308-315.

Benavides-Cordoba, V., Aviles, S., Ascuntar, C., Orozco, L., Mosquera, R., & Rivera, J. (2020).
Dual use of bronchodilators versus monotherapy, and its impact on pulmonary rehabilitation in
COPD patients. Pulmonary Pharmacology & Therapeutics, 61, 101898.

Benavides-Cordoba, V., Weil, M. S. M., Castaño, S., & Palacios, M. (2019). Hemodynamical
effects of metformin and sildenafil in the treatment of experimental pulmonary hypertension.
European Respiratory Journal. 54: PA4752

Betancourt-Peña J., Ávila Valencia, J. C., Assis, J. K., Gutiérrez, H. H., & Benavides-Cordoba,
V. (2019). Benefits of Pulmonary Rehabilitation in Patients with COPD with Use and without the
Use of Supplemental Oxygen During Exercise. Current Respiratory Medicine Reviews, 15(4),
281-288.

Ávila-Valencia, J. C., Hurtado-Gutiérrez, H., Benavides-Córdoba, V., & Betancourt-Pena, J.
(2019). Aerobic exercise in patients with heart failure with and without ventricular dysfunction in
a cardiac rehabilitation programme. Revista Colombiana de Cardiología, 26(3), 162-168.

Betancourt-Peña, J., Benavides-Córdoba, V., Avila-Valencia, J. C., & Rosero-Carvajal, H. E.
(2019). Differences Between COPD Patients of a Pulmonary

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Published
2020-05-14
Submitted
2020-04-09
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How to Cite
Benavides-Cordoba, V. (2020). Drug Repositioning for COVID-19. Colombia Médica, 51(2), e-4279. https://doi.org/10.25100/cm.v51i2.4279
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Vol 51 No 2 (2020): Coronavirus disease 2019
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Reviews

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