Cancer incidence and mortality in Uruguay: 2013-2017
Abstract
Background: Uruguay has the highest cancer incidence and mortality rates in Latin America. The National Cancer Registry of Uruguay, which has been in operation since 1992, provides epidemiological information on incidence and mortality at the country level.
Objective: The objective of this article is to update the incidence and mortality figures by reporting the information for the period 2013-2017.
Methods: All incident cases of invasive neoplasias except non-melanoma of the skin and all cancer deaths that occurred from 2013 to 2017 were analyzed. Age-standardized rates were calculated by the direct method, using the world standard population. Complementary, incidence (2002-2017) and mortality (1990-2017) trends were studied for the leading sites.
Results: Among females, the most common cancers are breast, colon and rectum, lung, cervix and thyroid. The most frequent cancers in males are prostate, lung, colon and rectum, bladder and kidney. Lung, prostate and colorectal cancer are the leading causes of cancer death in males while breast cancer is the first cause of cancer death among females.
Conclusions: Although cancer mortality has declined monotonously since 1990, cancer control is a challenge for Uruguay, wherein breast, lung and prostate cancer have very high incidence while the country must still make an effort to reduce other cancers that are very common in economically less favored countries.
Authors
Downloads
Keywords
- Incidence
- Cause of Death
- Uruguay
- Breast Neoplasms
- Censuses
- Mortality, Premature
- Prostatic Neoplasms
- Colorectal Neoplasms
- Life Expectancy
References
Bray F. The Evolving Scale and Profile of Cancer Worldwide: Much Ado About Everything. Cancer Epidemiol Biomarkers Prev. 2016;25(1):3-5. https://doi.org/10.1158/1055-9965.EPI-15-1109
Ferlay J, Ervik M, Lam F, Colombet M, Mery L, Piñeros M, et al. Cancer today [Internet]. Global Cancer Observatory: Cancer Today. Lyon, France: International Agency for Research on Cancer. 2020 [cited 2021 May 15]. Available from: http://gco.iarc.fr/today/home
Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA: A Cancer Journal for Clinicians. 2021;71(3):209-49. https://doi.org/10.3322/caac.21660
Rofman R, Amarante V, Apella I, editores. Cambio demográfico y desafíos económicos y sociales en el Uruguay del siglo XXI [Internet]. CEPAL, Naciones Unidas; 2016 [cited 2017 May 16]. Available from: http://repositorio.cepal.org/handle/11362/39862
Ministerio de Salud. Estadísticas Vitales [Internet]. [cited 2017 May 16]. Available from: http://www.msp.gub.uy/EstVitales/#services
Instituto Nacional de Estadística. Censos 2011 [Internet]. 2012 [cited 2016 Oct 5]. Available from: http://www.ine.gub.uy/censos-2011
Life expectancy at birth, total (years) - Uruguay | Data [Internet]. [cited 2021 Jul 1]. Available from: https://data.worldbank.org/indicator/SP.DYN.LE00.IN?locations=UY
Human Development Reports. El Índice de Desarrollo Humano (IDH) | [Internet]. [cited 2017 May 31]. Available from: http://hdr.undp.org/es/content/el-%C3%ADndice-de-desarrollo-humano-idh
Fritz A et al. International Classification of Diseases for Oncology. 3rd ed. Geneva: World Health Organization; 2000.
Ferlay J, Burkhard C, Whelan S, Parkin DM. CHECK AND CONVERSION PROGRAMS CHECK AND CONVERSION PROGRAMS. [cited 2016 Jun 29]; Available from: http://ihvnigeria.org/ihvnweb/webnew/rokdownloads/Cancer%20Registration%20Training%20lectures/Check%20and%20Conversion%20Programs%20for%20Cancer%20Registries.pdf
Instituto Nacional de Estadística. Censos 1963-1996 - [Internet]. 1997 [cited 2016 Oct 3]. Available from: http://www.ine.gub.uy/web/guest/censos-1963-1996
Instituto Nacional de Estadística. Censo 2004 Fase I [Internet]. 2005 [cited 2016 Nov 8]. Available from: http://www.ine.gub.uy/web/guest/censo-2004-fase-i
Segi M. Cancer Mortality for Selected Sites in 24 Countries (1950-57). Department of Public Health, Tohoku University of Medicine, Sendai, Japan. 1960;
Kim HJ, Fay MP, Feuer EJ, Midthune DN. Permutation tests for joinpoint regression with applications to cancer rates. Stat Med. 2000 Feb 15;19(3):335-51. https://doi.org/10.1002/(SICI)1097-0258(20000215)19:3<335::AID-SIM336>3.0.CO;2-Z
Statistical Methodology and Applications Branch,Survilliance Research Program, National Cancer Institute. Joinpoint Regression Program, Ver 4.7.0.0. Bethesda, Maryland, Estados UnidosUSA; 2019.
Number of Joinpoints [Internet]. Joinpoint Help System. [cited 2021 Sep 28]. Available from: https://surveillance.cancer.gov/help/joinpoint/setting-parameters/method-and-parameters-tab/number-of-joinpoints
Garau M, Musetti C, Alonso R, Barrios E. Trends in cancer incidence in Uruguay:2002 - 2015. Colombia Médica. 2019 Dec 30;50(4):224-38. https://doi.org/10.25100/cm.v50i4.4212
Ministerio de Salud Pública. Guía de práctica clínica de detección temprana del cáncer de mama. Tamizaje y diagnótico precoz [Internet]. 2015. Available from: https://www.gub.uy/ministerio-salud-publica/sites/ministerio-salud-publica/files/documentos/publicaciones/Iniciativas%20sanitarias%20%28guia%20deteccion%20cancer%20mama%29.pdf
Barrios E, Garau M. Cáncer: magnitud del problema en el mundo y en Uruguay, aspectos epidemiológicos. Anales de la Facultad de Medicina, Universidad de la República, Uruguay. 2017 Jun 8;4(1):9-46. https://doi.org/10.25184/anfamed2017.4.1.2
De Stefani E, Fierro L, Barrios E, Ronco A. Cancer mortality trends in Uruguay 1953-1991. Int J Cancer. 1994;56(5):634-9. https://doi.org/10.1002/ijc.2910560505
Lopez A, Collishaw N, Piha T. A descriptive model of the cigarette epidemic in developed countries. Tob Control. 1994 Sep;3(3):242-7. https://doi.org/10.1136/tc.3.3.242
Alonso R, Piñeros M, Laversanne M, Musetti C, Garau M, Barrios E, et al. Lung cancer incidence trends in Uruguay 1990-2014: An age-period-cohort analysis. Cancer Epidemiol. 2018;55:17-22. https://doi.org/10.1016/j.canep.2018.04.012
MSP aprobó reducción a dos dosis de vacuna HPV [Internet]. Ministerio de Salud Pública. [cited 2021 Jul 23]. Available from: https://www.gub.uy/ministerio-salud-publica/comunicacion/noticias/msp-aprobo-reduccion-dos-dosis-de-vacuna-hpv
Gonzalez Mora, Franco, Barbero Portela, Marcia. El control del tabaco en Uruguay en perspectiva histórica [Internet]. Ministerio de Salud Pública. 2020. Available from: http://cardiosalud.org/wp-content/uploads/2020/02/El_control_del_tabaco_en_Uruguay_web_final.pdf
Arnold M, Sierra MS, Laversanne M, Soerjomataram I, Jemal A, Bray F. Global patterns and trends in colorectal cancer incidence and mortality. Gut. 2017;66(4):683-91. https://doi.org/10.1136/gutjnl-2015-310912
Musetti C, Garau M, Alonso R, Piñeros M, Soerjomataram I, Barrios E. Colorectal Cancer in Young and Older Adults in Uruguay: Changes in Recent Incidence and Mortality Trends (in press). Int J Environ Res Public Health. 2021;18. https://doi.org/10.3390/ijerph18158232
Siegel RL, Torre LA, Soerjomataram I, Hayes RB, Bray F, Weber TK, et al. Global patterns and trends in colorectal cancer incidence in young adults. Gut. 2019 Dec;68(12):2179-85. https://doi.org/10.1136/gutjnl-2019-319511
Vuik FE, Nieuwenburg SA, Bardou M, Lansdorp-Vogelaar I, Dinis-Ribeiro M, Bento MJ, et al. Increasing incidence of colorectal cancer in young adults in Europe over the last 25 years. Gut. 2019 Oct;68(10):1820-6. https://doi.org/10.1136/gutjnl-2018-317592
PPNET, MSP. Second National Survey un Risk Factors for Non Comunicable Diseases - STEPS Methodology [Internet]. STEPS Collection. 2013. Available from: https://extranet.who.int/ncdsmicrodata/index.php/catalog/628
Fenocchi E, Martínez L, Tolve J, Montano D, Rondán M, Parra-Blanco A, et al. Screening for colorectal cancer in Uruguay with an immunochemical faecal occult blood test: European Journal of Cancer Prevention. 2006 Oct;15(5):384-90. https://doi.org/10.1097/00008469-200610000-00002
Ministerio de Salud Pública. Guía de práctica clínica de tamizaje de cáncer colo rectal [Internet]. 2018 [cited 2021 Jul 23]. Available from: https://www.gub.uy/ministerio-salud-publica/sites/ministerio-salud-publica/files/documentos/publicaciones/Gu%C3%ADa%20para%20el%20tamizaje%20del%20c%C3%A1ncer%20colo-rectal.pdf
RESUMENES ESTADISTICOS. Periodo 2013-2017 [Internet]. [cited 2021 Jul 23]. Available from: https://www.comisioncancer.org.uy/Ocultas/RESUMENES-ESTADISTICOS-Periodo-2013-2017-uc264
Nozar DMF, Briozzo L. Cáncer de cuello uterino en Uruguay. Controversias en la prevención. Rev Med Uru. 2017;33(1):64-70.
González V, Holcberg M, Díaz A, Duarte B, Deragón J, Duarte J, et al. Vacuna HPV: ¿la recomiendan los pediatras de diferentes prestadores de salud en Montevideo? Arch Pediatr Urug. 2021 Jun;92(1):10.
Balakrishnan M, George R, Sharma A, Graham DY. Changing Trends in Stomach Cancer Throughout the World. Curr Gastroenterol Rep. 2017 Aug;19(8):36. https://doi.org/10.1007/s11894-017-0575-8
Rawla P, Barsouk A. Epidemiology of gastric cancer: global trends, risk factors and prevention. pg. 2019;14(1):26-38. https://doi.org/10.5114/pg.2018.80001
Znaor A, Lortet-Tieulent J, Laversanne M, Jemal A, Bray F. International Variations and Trends in Renal Cell Carcinoma Incidence and Mortality. European Urology. 2015 Mar;67(3):519-30. https://doi.org/10.1016/j.eururo.2014.10.002
Znaor A, Laversanne M, Bray F. Less overdiagnosis of kidney cancer? an age-period-cohort analysis of incidence trends in 16 populations worldwide. Int J Cancer. 2017 May 23; https://doi.org/10.1002/ijc.30799
Powers AE, Marcadis AR, Lee M, Morris LGT, Marti JL. Changes in Trends in Thyroid Cancer Incidence in the United States, 1992 to 2016. JAMA. 2019 Dec 24;322(24):2440. https://doi.org/10.1001/jama.2019.18528
Li M, Maso LD, Vaccarella S. Global trends in thyroid cancer incidence and the impact of overdiagnosis. The Lancet Diabetes & Endocrinology. 2020 Jun;8(6):468-70. https://doi.org/10.1016/S2213-8587(20)30115-7
Forman D, Bray F, Brewster DH, Gombe Mbalawa C, Kohler B, Piñeros M, et al. Cancer Incidence in Five Continents, Vol. X. Lyon, France: International Agency for research on Cancer; 2014. (IARC Scientific publication N°164).
Bray F, Colombet M, Mery L, Piñeros M, Znaor A, Zanetti R, et al., editors. Cancer Incidence in Five Continents, Vol. XI. Lyon: International Agency for Research on Cancer.; 2017.

Copyright (c) 2022 Universidad del Valle

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
The copy rights of the articles published in Colombia Médica belong to the Universidad del Valle. The contents of the articles that appear in the Journal are exclusively the responsibility of the authors and do not necessarily reflect the opinions of the Editorial Committee of the Journal. It is allowed to reproduce the material published in Colombia Médica without prior authorization for non-commercial use