Nephrotic syndrome with a nephritic component associated with toxoplasmosis in an immunocompetent young man.
Abstract
Introduction: Although the association of infection by toxoplasmosis with the development of nephrotic syndrome is
uncommon, cases of this association have nevertheless been reported in the literature for more than two decades, not only
for congenital toxoplasmosis, but also in acquired cases, and occasionally in immunocompetent patients.
Development: A case is presented of an immunocompetent patient aged 15 with clinical and laboratory indications of
nephrotic/nephritic syndrome, in whom serological tests showed toxoplasma infection.
Conclusion: The presentation of nephrotic syndrome in ages where it is not commonly seen, leads to clinical suspicion of
secondary causes. Active search for possible causes should include
common tropical infections.
Authors
Downloads
Keywords
- Proteinuria
- renal disease
- Toxoplasma gondii
- immunocompetent
- mixed nephrotic syndrome.
References
Baum M. Pediatric glomerular diseases. Curr Opin Pediatr.
:137-9.
Alpers C. The Kidney. In: Kumar V, Abbas AK, Fausto N, Aster J,
eds. Robbins & Cotran Pathologic Basis of Disease. 7 ed. Saunders
Elsevier; 2012:982-3.
Gipson DS, Massengill SF, Yao L, Nagaraj S, Smoyer WE, Mahan
JD, et al. Management of Childhood Onset Nephrotic Syndrome.
Pediatrics. 2009;124(2):747-57.
Roth KS, Amaker BH, Chan JC. Nephrotic syndrome: pathogenesis
and management. Pediatr Rev. 2002;23(7):237-48.
van Velthuysen ML, Florquin S. Glomerulopathy associated
with parasitic infections. Clin Microbiol Rev. 2000;13(1):55-66,
table of contents.
Huldt G. Studies on experimental toxoplasmosis. Ann N Y Acad
Sci. 1971;177:146-55.
Shahin B, Papadopoulou ZL, Jenis EH. Congenital nephrotic
syndrome associated with congenital toxoplasmosis. J Pediatr.
;85(3):366-70.
Hill D, Dubey JP. Toxoplasma gondii: transmission, diagnosis
and prevention. Clin Microbiol Infect. 2002:634-40.
Montoya J BJ, Kovacs J. Toxoplasma gondii. In: Mandell GL,
Bennett JE, Dolin R, eds. Mandell, Douglas, and Bennett’s principles
and practice of infectious diseases. 7 ed. Elsevier; 2010:1112-
De Salvador-Guillouet F, Ajzenberg D, Chaillou-Opitz S, Saint-
Paul MC, Dunais B, Dellamonica P, et al. Severe pneumonia during
primary infection with an atypical strain of Toxoplasma gondii
in an immunocompetent young man. J Infect. 2006:e47-50.
Carme B, Bissuel F, Ajzenberg D, Bouyne R, Aznar C, Demar M,
et al. Severe acquired toxoplasmosis in immunocompetent adult
patients in French Guiana. J Clin Microbiol. 2002;40(11):4037-44.
- HTML
- NEPHROTIC SYNDROME MIXED ASSOCIATED WITH TOXOPLASMOSIS IN IMMUNOCOMPETENT
- NEPHROTIC SYNDROME MIXED ASSOCIATED WITH TOXOPLASMOSIS IN IMMUNOCOMPETENT
- NEPHROTIC SYNDROME MIXED ASSOCIATED WITH TOXOPLASMOSIS IN IMMUNOCOMPETENT
- NEPHROTIC SYNDROME MIXED ASSOCIATED WITH TOXOPLASMOSIS IN IMMUNOCOMPETENT
The copy rights of the articles published in Colombia Médica belong to the Universidad del Valle. The contents of the articles that appear in the Journal are exclusively the responsibility of the authors and do not necessarily reflect the opinions of the Editorial Committee of the Journal. It is allowed to reproduce the material published in Colombia Médica without prior authorization for non-commercial use
