Dengue in an area of the Colombian Caribbean
Main Article Content
Background: In Colombia, dengue is an endemic disease and the four serotypes have been reported. The objective of present study was to describe the frequency and severity of dengue in an area of the Colombian Caribbean (department of Cordoba)
Methodology: A retrospective study was conducted. Two data sources were analysed: The database from the Direction of Health in Córdoba, and clinical registers of patients diagnosed with haemorrhagic fevers and fevers of unknown origin in reference hospitals.
Results: The mean incidence of dengue between 2003-2010 was 36.5 cases per 105 inhabitants (CI95%: 34.3 – 37.5) and adjusted for sub-reporting, could be between 178.5 and 521.6. The mean incidence of severe dengue was 4.7 cases per 105 inhabitants (CI95%: 4.3 – 5.0). Mean mortality rate due to dengue was 0.3 cases per 105 inhabitants. The fatality rate was below 1%. The mean total leukocyte count in patients with dengue was 6181 mm3 (CI95%: 5973 – 6389) and with Severe Dengue it was 4729 mm3 (CI95%: 4220 – 5238). The average platelet count in patients with Dengue was 118,793/mm3 (CI95%: 107,255 – 130,331) and in patients with Severe Dengue 77,655 (CI95%: 59,640 - 95,670). Both differences were statistically significant (p< 0.05). The frequency of laboratories test per patient in patients with Dengue and Severe Dengue were different.
Conclusion: The department of Cordoba is a highly endemic zone of Dengue and Severe Dengue in the Colombian Caribbean.
Potts J, Gibbons R, Rothman A, Srikiatkhachorn A, Thomas S, Supradish P, et al. Prediction of dengue disease severity among pediatric Thai patients using early clinical laboratory indicators. PLoS Negl Trop Dis. 2010; 4(8): e769.
WHO . Dengue and severe dengue. WHO media centre; 2014. Accessed: 2011 Jan 15. Available from: http://www.who.int/mediacentre/factsheets/fs117/en/.
WHO . Dengue guidelines for diagnosis, treatment, prevention and control. Francia: World Health Organization, TDR; 2009. Accessed; 2011 Jan 15. Available from: http://whqlibdoc.who.int/publications/2009/9789241547871_eng.pdf.
Shepard DS, Coudeville L, Halasa YA, Zambrano B, Dayan GH. Economic impact of dengue illness in the Americas. Am J Trop Med Hyg. 2011; 84(2): 200–7.
Murillo-Llanes J, Soto-Valenzuela H, Flores-Flores P, Peraza-Garay F. Caracterización clínica y epidemiológica del dengue. Rev Med Inst Mex Seguro Soc. 2007; 45(5): 485–91.
Instituto Nacional de Salud,Dirección de Vigilancia y Análisis del Riesgo en Salud Pública Enfermedades Transmitidas por vectores. Boletín Epidemiológico Semanal. 2014; 53:17–22.
Camacho T , de la Hoz F, Cárdenas T, Sánchez C, de Calderón L, Pérez L, et al. Incomplete surveillance of a dengue-2 epidemic in Ibague, Colombia, 1995-1997. Biomedica. 2004; 24(2): 174–82.
DANE. Demografía y Población. Accessed: 20 August 2010; Available from: http://www.dane.gov.co/index.php/poblacion-y-demografia/proyecciones-de-poblacion.
Wilder SA, Gubler D. Geographic expansion of dengue: the impact of international travel. Med Clin North Am. 2008; 92(6): 1377–90.
Jansen C, Beebe N. The dengue vector Aedes aegypti: what comes next. Microbes Infect. 2010; 12(4): 272–9.
Añez G, Balza R, Valero N, Larreal Y. Economic impact of dengue and dengue hemorrhagic fever in the State of Zulia, Venezuela, 1997-2003. Rev Panam Salud Publica. 2006; 19(5): 314–20.
Ocazionez R, Gómez S, Cortés F. Serotipo, patrón de infección y dengue hemorrágico en área endémica colombiana. Rev Salud Pública. 2007; 9(2): 262–74.
Escobar MJ, Gómez DH. Determinantes de la transmisión de dengue en Veracruz: un abordaje ecológico para su control. Salud Pública Mex. 2003; 45(1): 43–53.
Penna G, Pinto L, Soranz D, Glatt R. High Incidence of diseases endemic to the Amazon region of Brazil, 2001-2006. Emerg Infect Dis. 2009; 15(4): 626–39.
Torres E. Dengue. Estudos Avançados. 2008; 22(64): 33–52.
Guha SD, Schimmer B. Dengue fever: new paradigms for a changing epidemiology. Emerg Themes Epidemiol. 2005; 2(1): 1–10.
Arbo A, Bogado N. Nuevas Guías de Tratamiento del Dengue. Pediatr (Asunción). 2011; 38(1): 7–8.
Salgado D, Vega M, Garzón M, Panqueba C, Rodriguez J. Mortalidad por dengue hemorrágico en niños en Colombia: más allá del choque. Infectio. 2008; 12(1): 247–53.
Villegas-Trejo A, Che-Mendoza A, González-Fernández M, Guillermo-May G, González-Bejarano H, Dzul-Manzanilla F, et al. Control enfocado deAedes aegypti en localidades de alto riesgo de transmisión de dengue en Morelos, México. Salud Pública Mex. 2011; 53(2): 141–51.
Salgado D, Rodríguez J, Garzón M, Cifuentes G, Ibarra M, Vega M, et al. Caracterización clínica y epidemiológica de dengue hemorrágico en Neiva, Colombia, 2004. Rev Salud Pública (Bogota). 2007; 9(1): 53–63.
Armien B, Suaya J, Quiroz E, Sah B, Bayard V, Marchena L, et al. Clinical characteristics and national economic cost of the 2005 dengue epidemic in Panama. Am J Trop Med Hyg. 2008; 79(3): 364–71.
Mamani E, Figueroa D, García M, Garaycochea MdelC, Pozo E. Infecciones concurrentes por dos serotipos del Virus dengue durante un brote en el noroeste de Perú, 2008. Rev Perú Med Exp Salud Publica. 2010; 27(1): 16–21.
Rey JR, Lounibos LP, Padmanabha H, Mosquera M. Resurgencia del dengue en América: pautas, procesos y prospectos. Interciencia. 2010; 35(11): 800–6.
Sánchez CR, Torres ZR, Segovia SF, Reyes VF, Alvarado MM, Fernández SI. Localización de criaderos no residenciales de Aedes aegypti y su asociación con casos de dengue en la zona Metropolitana de Monterrey, Nuevo León, Mexico. Rev Salud Pública Nutrición. 2010; 11(1): 1–6.
Ospina MC. Vigilancia epidemiológica del dengue en Antioquia. IATREIA. 2004; 17(3): 283–4.
Rivera A, Rodríguez A. Actualización en aspectos epidemiológicos y clínicos del dengue. Rev Cub Salud Pública. 2010; 36(1): 149–64.
Romero-Vivas C, Arango-Padilla P, Falconar A. Pupal-productivity surveys to identify the key container habitats of Aedes aegypti (L.)) in Barranquilla, the principal seaport of Colombia. Ann Trop Med Parasitol. 2006; 100(1): 87–95.
Ramírez ZM, Velasco MH, Ramos C, Peñuelas J, Maradiaga CM, Murillo LJ, et al. Caracterización clínica y epidemiológica de los casos de dengue: experiencia del Hospital General de Culiacán, Sinaloa, México. Rev Panam Salud Publica. 2009; 25(1): 16–23.
Acosta CB, Gómez IC. Biología y métodos diagnósticos del dengue. Rev Biomed. 2005; 16(2): 113–37.
Castrillón M, Iturrieta N, Cativelli S, Padilla F. Hallazgos ultrasonográficos en pacientes con Dengue. Revisión de la literatura. RAR. 2010; 74(1): 70–6.
Ramírez J, Aguirre A, Velandia R, Rosero H, García R, Ospina J, et al. Fiebre por dengue: guías de manejo. Rev Med Risaralda. 2010; 16(1): 41–51.
Pizarro D. Dengue, Dengue hemorrágico. Acta Pediátr Costarric. 2009; 21(1): 8–17.
Villar CL. El dengue: la epidemia se extiende y urgen intervenciones efectivas y herramientas clínicas para su atención. Infectio. 2008; 12(1): 9–10.
Kourí G, Pelegrino J, Munster B, Guzmán M. Sociedad, economia, inequidades y dengue. Rev Cubana Med Trop. 2007; 59(3): 177–85.
Gomez-Dantés H, Willoquet J. Dengue in the Americas: challenges for prevention and control. Cad Saude Publica. 2009; 25(1): 19–31.
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Accepted 2015-03-25
Published 2015-03-26
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