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Introducción:

Porphyromonas gingivalis es una bacteria asociadacon la periodontitis. Expresa una amplia gama de factores devirulencia, incluyendo las fimbrias, las cuales están codificadas porel gen FimA que representa seis genotipos conocidos.

Objetivo:

Identificar los genotipos de FimA de P. gingivalis enpacientes de Cali - Colombia , incluyendo la co -infección conAggregatibacter actinomycetemcomitans, Treponema denticola yTannerella forsythia.

Métodos:

Se obtuvieron muestras subgingivales de 151 individuoscon diferentes diagnósticos periodontales. La ocurrencia de P.gingivalis, los genotipos de FimA y otras bacterias se determinó porPCR.

Resultados:

Porphyromonas gingivalis fue positiva en 85 pacientes.El genotipo FimA II fue más prevalente, pero no hubo diferenciassignificativas entre los grupos de estudio (54.3%) , FimA IV fue elmás frecuente en la gingivitis (13.0%). Una alta correlación (p=0.000) se encontró entre P. gingivalis , T. denticola y T. forsythia.El genotipo FimA II estuvo correlacionado con la detección de T.denticola y T. forsythia.

Conclusiones:

Porphyromonas gingivalis tuvo una alta frecuenciaincluso en el grupo de individuos sanos. Se encontró una tendenciahacia una mayor frecuencia de FimA II en pacientes con periodontitismoderada y severa. El genotipo FimA II también se asoció con unamayor profundidad de la bolsa, una mayor pérdida de nivel deinserción, y con los pacientes en los que se detectó co-infección conT. denticola y T. forsythia

Adolfo Contreras, University of Valle, Cali Colombia. Periodontal Medicine Group.

Full Professor, School of Dentistry,
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Received 2014-03-03
Accepted 2015-09-16
Published 2015-09-30