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Authors

Objetive:

To establish association between socioeconomic status and plasmatic markers of lipoperoxidation and antioxidants in Venezuelan school-age children from the middle-class and in critical poverty.

Methods:

Cross-sectional study with a sample of 114 school-age children (aged 7-9). The socioeconomic status, dietary intake of macro and micro-nutrients, weight, height, lipid profile, indicators of lipid peroxidation and enzymatic and non-enzymatic antioxidants were determined.

Results:

The daily average intake of energy, carbohydrates and vitamin A, and the percentage of energy obtained from carbohydrates was significantly higher in middle-class children compared to critical poverty children (p <0.05). The circulating oxidized low density lipoprotein (p <0.001) and the susceptibility of low density lipoproteins and very low density lipoproteins to oxidation in vitro (p <0.05) were significantly higher in middle-class children, while the critical poverty children showed significantly lower levels of Vitamin C and E in plasma (p <0.05). Non-enzymatic antioxidant levels were frequently deficient in both strata. The concentrations of circulating oxidized low density lipoprotein (OR: 1.09, CI 95%: 1.016-1.179; p= 0.017) and Vitamin C (OR: 3.21, CI 95%: 1.104-9.938; p= 0.032) were associated to the socioeconomic status independently of gender, family history of premature coronary artery disease, triglicerides, Vitamin C and E dietary intake and count of white blood cells.

Conclusion:

The socioeconomic status was associated to circulating oxidized low density lipoprotein and Vitamin C in Venezuelan school-age children, The results suggested the need to improve the dietary intake of antioxidants in both studied socioeconomic groups.

 

 

Nelina Ruíz-Fernández, 1- Universidad de Carabobo, Valencia, Carabobo, Venezuela. 2- Instituto de Investigaciones en Nutrición (INVESNUT), Facultad de Ciencias de la Salud, Universidad de Carabobo, Valencia, Carabobo, Venezuela.

1- Departamento de Morfofisiopatología, Escuela de Bioanálisis de la Facultad de Ciencias de la Salud, Universidad de Carabobo, Valencia, Carabobo, Venezuela.

2- Instituto de Investigaciones en Nutrición (INVESNUT), Facultad de Ciencias de la Salud, Universidad de Carabobo, Valencia, Carabobo, Venezuela.

Virgilio Bosch Román, Universidad Central de Venezuela, Caracas, Venezuela.

Sección de Lipidología del Instituto de Medicina Experimental, Universidad Central de Venezuela, Caracas, Venezuela.

María Isabel Giacopini, Universidad Central de Venezuela, Caracas, Venezuela.

Sección de Lipidología del Instituto de Medicina Experimental, Universidad Central de Venezuela, Caracas, Venezuela.
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Received 2014-12-18
Accepted 2016-11-05
Published 2024-06-11