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Background: Reading of Papanicolaou test slides follows a pattern that could omit sectors with abnormal cell nests. A low-cost guided reading strategy has been designed.

Aim: To establish criteria validity and reproducibility of guided reading strategy in cervical uterine Pap smear.

Methodology: To each of 300 women without cervical cancer history in order to apply Papanicolaou test, two slides were taken; both slides were read by regular method, and then reevaluated in blinded conditions with a guided technique. Diagnosis accuracy of regular and guided techniques was determined using pathologist’s reading as a gold standard.

Results: When regular readings were used 65 (21.7%) of women had abnormal cytology, and 64 (21.3%) had also abnormal readings with the guided technique. Concordance of the regular reading (Kappa 0.354; 95% CI 0.250-0.457) improved with the guided technique (Kappa 0.395; 95% CI 0.285-0.505), while 24.3% slides were found abnormal in gold standard (2.7% with a high degree of malignancy). The guided reading improves all criteria validity indicators.

Conclusion: This study demonstrated that the guided reading improves criteria validity indicators, correcting some technician mistakes; however, a populational study is necessary to confirm these results.

Hernando Pardo, Liga Santandereana de Lucha contra el Cáncer

Director, Liga Santandereana de Lucha contra el Cáncer, Bucaramanga, Colombia.

Luis Alfonso Díaz, Universidad Autónoma de Bucaramanga, Bucaramanga

Profesor Asociado, Facultad de Medicina, Universidad Autónoma de Bucaramanga, Bucaramanga, Colombia.

María Eugenia Niño, Universidad Autónoma de Bucaramanga, Bucaramanga

Profesor Asociado, Facultad de Medicina, Universidad Autónoma de Bucaramanga, Bucaramanga, Colombia.
Pardo, H., Díaz, L. A., & Niño, M. E. (2006). Utility of a guided reading technique for cervical cancer screening. Colombia Medica, 37(2), 142–147. https://doi.org/10.25100/cm.v37i2.425

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