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Introduction: Pediatric gastroesophageal reflux disease (GERD), has a high morbidity-mortality. The gold standard is the 24 hours pHmetry (pH24h). The objective is to determine the relationship between symptoms and parameters of pH24h.
Methods: This is a comparative, descriptive, and retrospective study. N=35 children <14 years old suffering GERD, from the HUV in Cali, Colombia. Data: age, gender, symptoms and stature were taken. Children were divided into three groups: digestive (group 1), respiratory (group 2) and mixed (group 3). They were classified as chronic undernourished (deficit height/age >5%) according to tables from the NCHS. From pH24h were taken: reflux index (RI), number of acid episodes, number of episodes >5 min and duration of the longest episode and association with symptoms. The statistical analysis was the Student’s test t, having p<0.05 as significant.
Results: 35 children were included (47.9±41.3 months), 20 males, 2 with digestive symptoms, 17 with respiratory and 16 with both symptoms, with a deficit of H/A= 8.0±10.89%. 20 (57.1%) pH24h were abnormal by Vandenplas’ criterion: 12 in group 1, 1 in group 2 and 7 in group 3. The parameters of pH24h were: IR 5.25±4.94%; number of acid episodes 77.21±78.96; number of acid episodes >5 min 1.30±3.67 and the duration of the longest episode 9.36±20.06 min. There were no significant differences between the parameters of pH24h and the study groups (p>0.05). The respiratory group showed pH24h parameters more involved: IR 4.75±5.17%, number of acid episodes 79.17±79.76, number of acid episodes >5 min 2.29±4.97 and duration of the longest episode 15.0±27.04 min; the same as their nutritional status (p=0.003).
Conclusion: There was no significant association between pH24h parameters and symptoms; however, respiratory symptoms group had a higher compromise of the pH24h parameters and nutritional status.

Carlos Alberto Velasco, Universidad del Valle

Profesor Titular, Universidad del Valle. Docente investigador, Universidad Libre Seccional Cali. Docente Universidad Autónoma de Occidente. Director Grupo de Investigación GASTROHNUP, Cali, Colombia.

Grupo de Investigación en Gastroenterología, Hepatología y Nutrición Pediátrica (GASTROHNUP), Cali, Colombia.

Ángelo Giovanni Valencia, Universidad del Valle

Médico Pediatra, Universidad del Valle, Cali, Colombia.

Maira Patricia Sánchez, Instituto Nacional de Pediatría

Estudiante postgrado en gastroenterología pediátrica, Instituto Nacional de Pediatría, Ciudad de México, México.

Grupo de Investigación en Gastroenterología, Hepatología y Nutrición Pediátrica (GASTROHNUP), Cali, Colombia.

Velasco, C. A., Valencia, Ángelo G., & Sánchez, M. P. (2007). Digestive and respiratory symptoms and parameters of 24 hours pHmetry in children with pediatric gastroesophageal reflux disease. Colombia Medica, 38(1 Supl 1), 14–18. Supl 1.482


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