Genetic diversity in human populations of two regions from Colombia.
mtDNA STR’s Amerindian populations Genetics diversity Mixed population Genetics flow Colombia southwest
Main Article Content
Introduction: Preliminary studies have showed close relations among southwest human populations and Andean region leaving it consequences in ethnic admixe process. However, this wide process of racial admixture today it is not exist sufficient information to define structure and genetic diversity for each region and Colombian population in general.
Objectives: The principal goal from this study was to determinate the genetic structure and diversity present into human populations from Andean and Southwest Colombia regions.
Methods: This study was realized by characterization allelic frequencies of 12 autosomal STR’s and six RFLP’s of mtDNA presents in 472 individuals from three ethnics groups: Caucasoids, Afroamericans and Amerindians.
Results: mtDNA haplotypes presents in Afrodescends sample was 15% and 43% typical Amerindian and African markers respectively; the genetics diversity analysis shows a value of 0.72 in Pijao indigenous, these values are close to diversity index of mestizos from Cali (0.75). AMOVA of allelic frequencies from 12 STR’s shows that genetic structures don’t was significatively different (FST de 0.032); in addition it’s to exhibit high endogamy in mestizos from Caldas sample (0.43) and Coyaima indigenous (0.34).
Conclusions: was established genetic structure for southwest Colombian population. Additionally, the results confirm the mixing process and the genetics flow among many populations groups from Andean and southwest Colombia regions.
Objectives: The principal goal from this study was to determinate the genetic structure and diversity present into human populations from Andean and Southwest Colombia regions.
Methods: This study was realized by characterization allelic frequencies of 12 autosomal STR’s and six RFLP’s of mtDNA presents in 472 individuals from three ethnics groups: Caucasoids, Afroamericans and Amerindians.
Results: mtDNA haplotypes presents in Afrodescends sample was 15% and 43% typical Amerindian and African markers respectively; the genetics diversity analysis shows a value of 0.72 in Pijao indigenous, these values are close to diversity index of mestizos from Cali (0.75). AMOVA of allelic frequencies from 12 STR’s shows that genetic structures don’t was significatively different (FST de 0.032); in addition it’s to exhibit high endogamy in mestizos from Caldas sample (0.43) and Coyaima indigenous (0.34).
Conclusions: was established genetic structure for southwest Colombian population. Additionally, the results confirm the mixing process and the genetics flow among many populations groups from Andean and southwest Colombia regions.
Rondón, F., Osorio, J. C., Peña, Ángela V., Garcés, H. A., & Barreto, G. (2008). Genetic diversity in human populations of two regions from Colombia. Colombia Medica, 39(2 Supl 2), 52–60. https://doi.org/10.25100/cm.v39i2 Supl 2.585
Downloads
Download data is not yet available.
- Laura Cifuentes-C, Ana Lucia Rivera-Herrera, Guillermo Barreto, BRCA1 and BRCA2 mutations in breast and ovarian cancer families from south west Colombia , Colombia Medica: Vol. 50 No. 3 (2019)
- Martha Lucía Hincapié, Adriana María Gil, Adriana Lucía Pico, Leonor Gusmäo, Fernando Rondón, Clara Inés Vargas, Adriana Castillo, Análisis de la estructura genética en una muestra poblacional de Bucaramanga, departamento de Santander , Colombia Medica: Vol. 40 No. 4 (2009)
- Yamid Braga, Leonardo Arias B., Guillermo Barreto, Diversity and genetic structure analysis of three Amazonian Amerindian populations from Colombia , Colombia Medica: Vol. 43 No. 2 (2012)
The copy rights of the articles published in Colombia Médica belong to the Universidad del Valle. The contents of the articles that appear in the Journal are exclusively the responsibility of the authors and do not necessarily reflect the opinions of the Editorial Committee of the Journal. It is allowed to reproduce the material published in Colombia Médica without prior authorization for non-commercial use