H-Y antigen and primary sex determination
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The primary determination of sex in mammals appears under the control of locus H-Y by the activity of its antigen H-Y. Testicular organization depends more on the antigen in the gonads than on the presence of the Y chromosome. It is thus important to determine the antigen in sexual maldefinitions to confirm the presence of the testes.
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- Jairo A. De la Cruz, Edgar E. Delgado, Stella de Lozada, Testicular feminization associated to reciprocal translocation , Colombia Medica: Vol. 19 No. 4 (1988)
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