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The primary determination of sex in mammals appears under the control of locus H-Y by the activity of its antigen H-Y. Testicular organization depends more on the antigen in the gonads than on the presence of the Y chromosome. It is thus important to determine the antigen in sexual maldefinitions to confirm the presence of the testes.

Jairo A. De la Cruz, Profesor Asociado, Departamento de Morfología, División de Salud, Universidad del Valle, Cali, Colombia.

Profesor Asociado, Departamento de Morfología, División de Salud, Universidad del Valle, Cali, Colombia.

Jairo A. De la Cruz. (1981). H-Y antigen and primary sex determination. Colombia Medica, 12(3), 137–140. https://doi.org/10.25100/cm.v12i3.6019

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