Estimación del tiempo de muerte por análisis bioquímico del humor vítreo humano
Keywords:
sodio, potasio, Hospital Universitario del Valle, tiempo de muerteMain Article Content
From corpses received at the morgue of Hospital Universitario del Valle in Cali, Colombia, 115 bilateral post-mortem samples of vitreous humor were obtained and analyzed for sodium and potassium concentrations. A high correlation index of 0.85 was found for potassium and time of death in linear regression analysts, which was statistically significant (p < 0.0000001). The incorporation of sodium concentration in the model proves its predictive power, suggesting the need to analyze the effect, in similarly conducted studies, of other substances, such as glucose, urea nitrogen, and chloride, previously discarded in literature. No statistical difference was found between samples from both eyes. This test can be useful in medico-legal cases in which a more precise estimation of time of death is considered necessary.
Vargas, E. Medicina legaL Pp. 68-75. Lehmann Editores, Costa Rica, 1983.
Leahy, MS & Farber, ER Changes of potassium concentration in the vitreous humor after death. J Foren. sfc Set. 1967, 12: 214-222.
Stumer, WQ & Gantner, GE. Toe postmortem interval. AmJ ClinPathol, 1964, 42: 137-144. DOI: https://doi.org/10.1093/ajcp/42.2.137
Agrawal, RL, Gupta, PC, Bhasiri, S & Nagar, CK. Determination of the time of death by estimating potassium level in the cadaver vitreous humor. lndian J Ophthalmol, 1983, 31: 528-531.
Sturner, WQ. Toe vitreous humour: post-mortem potassium changes . La.ncet, 1963, 1: 807-808 . DOI: https://doi.org/10.1016/S0140-6736(63)91509-5
Corn, IJ. Post-mortem chemistrles on human vitreous humor. Am J Clin Pathol, 1969, 51: 741-749. DOI: https://doi.org/10.1093/ajcp/51.6.741
Swift, PGF, Worthy, E & Emery, JL. Biochemical state of the vitreous humor of infants at necropsy. Arch Dis Child, 1974, 49: 680-685. DOI: https://doi.org/10.1136/adc.49.9.680
Bray, M, Luke, J & Br1an, DB. Vitreous humor chemistry in deaths associated with rapid chilling and prolonged freshwater immersion. J Forensic Se(, 1983, 28: 588-593 DOI: https://doi.org/10.1520/JFS11553J
Farmer, JG, Benomran, F, Watson, M & Herland, WA. Magnesium, sodium and calcium in post-mortem vitreous humor from humans. Forensic Set lnt, 1985, 27: 1-13. DOI: https://doi.org/10.1016/0379-0738(85)90099-4
O. Balassooriya, BAW, Hill, ST & Williams, AR The biochemistry of vitreous humor. A comparative study of the potassium, sodium, and urate concentration in the eyes at identical time intervals after death; Forensic Set lnt, 1984, 26: 85-91. DOI: https://doi.org/10.1016/0379-0738(84)90064-1
Colton, T. Estadistica en medicina. Pp. 199-219. Salvat Editores SA, Barcelonas, 1979.
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