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Recently, molecular and epidemiological studies have shown an etiologic role for human papillomavirus (HPV) in a subset of upper aero-digestive tract (UADT) cancers in women and men. Oral HPV infections acquired through oral sex seems to be the main risk factor for HPV-associated oral cancers. The high-risk type HPV-16 was the most prevalent infection HPV-positive in most oral cancers. Therefore, the prophylactic vaccine against HPV-16 could prevent HPV associated oral cancer if the vaccine were demonstrated to be capable of preventing oral HPV-16 infection. Thus, these findings have created new potential opportunities for the primary prevention of oral cancers.
Castillo, A. (2011). HPV infection and carcinogenesis in the upper aero-digestive tract. Colombia Medica, 42(2), 233–242.


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Received 2011-06-13
Accepted 2011-06-13