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Porphyromonas gingivalis is implicated in chronic and aggressive periodontitis. This bacterium has numerous virulence factors and one is the fimbriae, which is quite important for bacterial colonization. Fimbriae are appendices that anchor to the bacterial wall and are comprised of the protein fimbriline encoded by the fimA gene. Thus far, six genotypes have been identified, fimA I to V and Ib. Genotypes II and IV are associated with periodontal disease, while genotype I is related to gingival health. Genotype identification of P. gingivalis fimA in periodontitis would be important to confirm the pathogenic genotypes and to establish risk at population level. This review is about the P. gingivalis fimA genotype prevalence worldwide. A systematic search using Pubmed, Hinary, and Science Direct within the following descriptors: Porphyromonas gingivalis, bacterial adhesion,periodontitis, fimbriae, fimA, genotipification was performed to April 2011.

Sandra M Moreno, Profesor contratista

DDS Univesidad del Valle, Cali Colombia.

Magister Student in biomedics science, Universidad del Valle.

Periodontal medicine group member. Universidad del Valle

 

Adolfo Contreras, Profesor Titular Escuela de Odontología

Phd Craneofacial Biology – University of Southern California – Los Angeles – USA - 1999

Magister in Biomedics science – Universidad del Valle – Cali – Colombia - 1993

DDS Universidad del Valle – Cali – Colombia 1984

Periodontal medicine Investigation group director. Universidad del Valle

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Received 2011-07-15
Accepted 2011-11-22
Published 2013-03-12