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Case Description: A 52-year-old female patient was admitted to our clinic with complaints of cough, sputum, fever and fatigue. The patient has been receiving immunosuppressive therapy for thrombocytopenic purpura for 5 years.


Clinical Finding: Inspiratory crackles were heard on both hemithorax. Oxygen saturation measured with the pulse oximeter was 97%. Chest X-ray showed diffuse reticular opacities that were more prominent in the upper zones of both lungs. WBC counts were 17600/mm3 and Platelet counts were 29000/mm3. Thorax CT showed that there were many thin-walled cavities and millimetric nodules accompanied by ground-glass infiltrates in the upper and middle lobes. Gram staining of bronchial fluid, taken by bronchoscopy, revealed Gram-negative bacilli and intense polymorphonuclear leukocytes. The bacteria were defined as Delftia acidovorans by BD Phoenix automated system.


Treatment and outcomes: The patient was hospitalized with suspicion of opportunistic pulmonary infections and cavitary lung disease. After the empirical treatment of intravenous piperacillin-tazobactam and oral clarithromycin, her clinical and radiological findings significantly regressed, and she was discharged with outpatient follow-up.


Clinical Relevance: This is the first example of cavitary pneumonia due to Delftia acidovorans in an immunocompromised patient. We would like to emphasize that Delftia pneumonia should be considered in the differential diagnosis of pulmonary cavitary involvement in such patients.

Aysel Sünnetçioğlu, Van Yuzuncu Yil University, Faculty of Medicine, Department of Chest Medicine, Tuşba/Van, Turkey

Van Yuzuncu Yil University, Faculty of Medicine, Department of Chest Medicine, Tuşba/Van, Turkey

AAA_orcid_id28.png https://orcid.org/0000-0002-3379-3620

Selami Ekin, Van Yuzuncu Yil University, Faculty of Medicine, Department of Chest Medicine, Tuşba/Van, Turkey

Van Yuzuncu Yil University, Faculty of Medicine, Department of Chest Medicine, Tuşba/Van, Turkey

AAA_orcid_id29.png https://orcid.org/0000-0001-5922-0348

İrfan Baran, Van Yuzuncu Yil University, Faculty of Medicine, Department of Infectious Disease, Tuşba/Van, Turkey

Van Yuzuncu Yil University, Faculty of Medicine, Department of Infectious Disease, Tuşba/Van, Turkey

AAA_orcid_id30.png https://orcid.org/0000-0003-3341-9898

Mesut Özgökçe, Van Yuzuncu Yil University, Faculty of Medicine, Department of Radiology, Tuşba/Van, Turkey

Van Yuzuncu Yil University, Faculty of Medicine, Department of Radiology, Tuşba/Van, Turkey

AAA_orcid_id31.png https://orcid.org/0000-0002-3095-2446

Selvi Aşker, Van Yuzuncu Yil University, Faculty of Medicine, Department of Chest Medicine, Tuşba/Van, Turkey

Van Yuzuncu Yil University, Faculty of Medicine, Department of Chest Medicine, Tuşba/Van, Turkey

AAA_orcid_id32.png https://orcid.org/0000-0003-4077-8549

İbrahim Üney, Van Yuzuncu Yil University, Faculty of Medicine, Department of Chest Medicine, Tuşba/Van, Turkey

Van Yuzuncu Yil University, Faculty of Medicine, Department of Chest Medicine, Tuşba/Van, Turkey

AAA_orcid_id33.png https://orcid.org/0000-0002-8801-7661

Engin Turgut, Van Yuzuncu Yil University, Faculty of Medicine, Department of Internal Medicine, Tuşba/Van, Turkey

Van Yuzuncu Yil University, Faculty of Medicine, Department of Internal Medicine, Tuşba/Van, Turkey

AAA_orcid_id35.png https://orcid.org/0000-0001-7451-7270

Sümeyye Akyüz, Van Yuzuncu Yil University, Faculty of Medicine, Medical Microbiology Department, Tuşba/Van, Turkey,

Van Yuzuncu Yil University, Faculty of Medicine, Medical Microbiology Department, Tuşba/Van, Turkey,

AAA_orcid_id37.png https://orcid.org/0000-0003-1999-7827

YILDIZ, H., Sünnetçioğlu, A., Ekin, S., Baran, İrfan, Özgökçe, M., Aşker, S., Üney, İbrahim, Turgut, E., & Akyüz, S. (2024). Delftia Acidovorans pneumonia with lung cavities formation. Colombia Medica, 50(3), 215–21. https://doi.org/10.25100/cm.v50i3.4025

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