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Introduction: cancer represents a challenge for global public health, since it requires a comprehensive, transdisciplinary, and sustainable strategy for its control. In this context, epidemiological surveillance systems, such as Population-Based Cancer Registries (PBCR), become key actors for the development and monitoring of the implemented actions.

Objective: within the framework of the national cancer plan proposed in 2017 for the country, this study analyze the trend in cancer incidence and mortality rates during the period 1985-2017.

Methods: age-standardized incidence and mortality rates were estimated using data from PBCR of Quito. For the analysis of the trends, of selected locations, joinpoint regression and Average Annual Percent Change (AAPC) was used.

Results: A sustained increase in cancer incidence (AAPC Men= 1.5%, 95% Confidence Interval [CI]: 1.2 - 1.7; AAPC Women: 0.7%, 95% CI: 0.4 - 1.0) and mortality rates (AAPC Men= 2.0%, 95% CI: 1.8 - 2.3; AAPC Women= 1.3%, 95% CI: 1.1 - 1.6) was observed in Quito throughout the study period. There was a sustained increase in incidence and mortality rates of breast, prostate, colon-rectum, thyroid and lymphoma cancers. While the incidence rates of cancer of the cervix and stomach, related to infectious agents, decreased.

Conclusion: The information presented by the PBCR of Quito serves as a reference for the prognosis of cancer in the country and as a baseline for its control. Actions to strengthen prevention and promotion strategies against cancer are urgent, especially in breast and cervix cancer, to mitigate its impact on Ecuadorian society.

Patricia Cueva, Sociedad de Lucha contra el Cáncer, Registro Nacional de Tumores, Quito - Ecuador, Ecuador


Wilmer Tarupi, Sociedad de Lucha contra el Cáncer, Registro Nacional de Tumores, Quito - Ecuador, Ecuador


Henry Caballero, Sociedad de Lucha contra el Cáncer, Registro Nacional de Tumores, Quito - Ecuador, Ecuador


Cueva, P., Tarupi, W., & Caballero, H. (2023). Cancer incidence and mortality in Quito: information to monitor cancer control policies. Colombia Medica, 53(1), e2024929. (Original work published April 25, 2022)

Gelband H, Sankaranarayanan R, Gauvreau CL, Horton S, Anderson BO, Bray F, et al. Costs, affordability, and feasibility of an essential package of cancer control interventions in low-income and middle-income countries: key messages from Disease Control Priorities. Lancet. 2016; 387(10033): 2133-2144.

Vaccarella S., Lortet-Tieulent J., Saracci R., Fidler M., Conway D., Vilahur N., Sarfati D., Jemal A. Mackenbach J., Marmot M., Straif K., Wild C. Reducing Social Inequalities in Cancer: Setting Priorities for Research. Ca Cancer J Clin. 2018; 68:324-326.

Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, Bray F. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. 2021; 71(3): 209-249.

World Health Organization. World Health Assembly, 70‎. Cancer prevention and control in the context of an integrated approach. World Health Organization; 2017.

Piñeros M, Abriata MG, Mery L, Bray F. Cancer registration for cancer control in Latin America: a status and progress report. Rev Panam Salud Publica. 2017;41:e2.

World Health Organization. Sixty-sixth World Health Assembly. Draft comprehensive global monitoring framework and targets for the prevention and control of noncommunicable disease. Geneva: WHO; 2013. Available from: http://apps.

Corral F., Cueva P., Yépez J., Tarupi W. Trends in cancer incidence and mortality over three decades in Quito - Ecuador. Colombia Médica (Cali). 2018; 49(1):35-41

República del Ecuador, Registro Oficial 784. Acuerdo Ministerial 6345. Ecuador; 1984

INEC. Resultados del Censo 2010 de población y vivienda en el Ecuador. Quito; 2011. Disponible en:

Piñeros M, Abriata MG, de Vries E, Barrios E, Bravo LE, Cueva P, et al. Progress, challenges and ways forward supporting cancer surveillance in Latin America. Int J Cancer. 2021; 149(1): 12-20.

Cueva AP, Yépez MJ, Tarupi W. Epidemiología del Cáncer en Quito 2011-2015. 16 ed. Sociedad de Lucha contra el Cáncer, Registro Nacional de Tumores: Quito; 2019. Disponible en:

Segi M, Nippon TK, Tōhoku DI. Cancer Mortality for Selected Sites in 24 Countries (1950-57). Departmen tof Public Health Tohoku University School of Medicine; 1960.

National Cancer Institute. Joinpoint Trend Analyses software; 2015.

Ministerio de Salud Pública. Estrategia Nacional para la Atención Integral del Cáncer en el Ecuador. Quito, Ecuador; 2017. Disponible en:

Pilleron S, Sarfati D, Janssen-Heijnen M, Vignat J, Ferlay J, Bray F, et al. Global cancer incidence in older adults, 2012 and 2035: A population-based study. Int J Cancer. 2019; 144(1): 49-58.

Tarupi W, de Vries E, Cueva P, Yépez J. Stagnation in Decreasing Gastric Cancer Incidence and Mortality in Quito: Time Trend Analysis, 1985-2013. J Cancer Epidemiol. 2019; 2019: 1504894.

Assumpção PP, Fernandes BW, Ishak G, Gonzaga VCL, Fernandez CFJ, Carioca FH, et al. The diffuse-type gastric cancer epidemiology enigma. BMC Gastroenterol. 2020; 20: 223.

Vaccarella S, Lortet-Tieulent J, Saracci R, Conway DI, Straif K, Wild CP. Reducing social inequalities in cancer: evidence and priorities for research. IARC Scientific Publication No. 168. Lyon, France: International Agency for Research on Cancer. 2019. Available from:

Tarupi W, Guarnizo C, de Vries E. Educational inequalities in gastric cancer incidence and mortality, Quito 1996-2013. International Association of Cancer Registries, Annual Conference; Arequipa, Peru.

Organización Mundial de la Salud. Convenio Marco para el Control del Tabaco - Protocolo para la eliminación del comercio ilícito de productos de tabaco. Geneva; 2013

Freire WB, Ramírez-Luzuriaga MJ, Belmont P, Mendieta MJ, Silva-Jaramillo MK, Romero N, et al. Tomo I: Encuesta Nacional de Salud y Nutrición de la población ecuatoriana de cero a 59 años. ENSANUT-ECU 2012. Ministerio de Salud Pública/Instituto Nacional de Estadísticas y Censos. Quito-Ecuador; 2014. Disponible en:

Montes SE. Detección y control de cáncer de cuello uterino. ElHospital; 2005. Ciado: 2021 mayo. Disponible en:

Ruales J, Checa F. La atención del cáncer en el Ecuador: pasado, presente y future. Rev Fac Cien Méd. 2018; 43(1) :46-59.

Arbyn M, Weiderpass E, Bruni L, de Sanjosé S, Saraiya M, Ferlay J, Bray F. Estimates of incidence and mortality of cervical cancer in 2018: a worldwide analysis. Lancet Glob Health. 2020 Feb;8(2):e191-e203.

OMS. Estrategia mundial para acelerar la eliminación del cáncer del cuello uterino como problema mundial de salud pública y sus objetivos y metas conexos para el periodo 2020-2030. OMS; 2020. Disponible en:

Li M, Dal Maso L, Vaccarella S. Global trends in thyroid cancer incidence and the impact of overdiagnosis. Lancet Diab Endocrinol. 2020; 8(6): 468-470.

Vaccarella S, Franceschi S, Bray F, Wild CP, Plummer M, Dal Maso L. Worldwide Thyroid-Cancer Epidemic? The Increasing Impact of Overdiagnosis. N Engl J Med. 2016; 375(7): 614-7.

Borges AKDM, Miranda-Filho A, Koifman S, Koifman RJ. Thyroid cancer incidences from selected south america population-based cancer registries: an age-period-cohort study. J Glob Oncol. 2018; 4: 1-11.

Zhou CK, Check DP, Lortet-Tieulent J, Laversanne, M, Jemal A, Ferlay J, et al. Prostate cancer incidence in 43 populations worldwide: an analysis of time trends overall and by age group. Int J Cancer. 2016; 138:1388-1400.

US Preventive Services Task Force, Grossman DC, Curry SJ, Owens DK, Bibbins-Domingo K, Caughey AB, Davidson KW, et al. Screening for prostate cancer: US Preventive Services Task Force recommendation statement. JAMA. 2018;319:1901-1913.

Bray F, Piñeros M. Cancer patterns, trends and projections in Latin America and the Caribbean: a global context. Salud Publica Mex. 2016; 58(2): 104-17.

World Cancer Research Fund; American Institute for Cancer Research. The Continuous Diet, Nutrition, Physical Activity and Cancer: Colorectal Cancer. Update Project Expert Report; 2017. Accessed: 2020 October 23.

Cuesta CWP. Prueba de sangre oculta en tamizaje de cáncer colorrectal, método inmunoquímico frente al guayacol pacientes 50 a 75 años, HPAS-2018. Tesis pregrado. Carrera de Bioquímica Clínica, Facultad de Ciencias Químicas, Universidad Central del Ecuador: Quito, 2019.

Montalvo TMA, Echeverria R. Detección temprana del Cáncer Colorrectal mediante la estrategia de tamizaje protocolizada en personas entre los 50 y 75 años de edad asintomáticos en el área de influencia del Hospital Pablo Arturo Suárez. Especialista en Gerencia de Salud, Colegio de Posgrados, Escuela de Salud Pública. Universidad San Francisco de Quito. Quito, 2014.

Ministerio de Salud Pública del Ecuador. Tamizaje de cáncer colorrectal mediante sangre oculta en heces fecales por método inmunoquímico cuantitativo, más colonoscopia, biopsia y estudio histopatológico en la población ecuatoriana entre 50 y 75 años de edad. Manual. Quito: Ministerio de Salud Pública, Dirección Nacional de Estrategias de Prevención y Control, MSP; 2017

Miranda-Filho A, Piñeros M, Ferlay J, Soerjomataram I, Monnereau A, Bray F. Epidemiological patterns of leukaemia in 184 countries: a population-based study. Lancet Haematol. 2018 Jan;5(1): e14-e24.

Miranda-Filho A, Piñeros M, Znaor A, Marcos-Gragera R, Steliarova-Foucher E, Bray F. Global patterns and trends in the incidence of non-Hodgkin lymphoma. Cancer Causes Control. 2019; 30(5): 489-499.

Vineis P, Wild CP. Global cancer patterns: causes and prevention. Lancet. 2014; 383(9916): 549-57.

Vaccarella S, Lortet-Tieulent J, Saracci R, Fidler M, Conway D, Vilahur N, et al. Reducing social inequalities in cancer: setting priorities for research. Ca Cancer J Clin. 2018; 68: 324-326.


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Received 2021-06-30
Accepted 2021-11-25
Published 2023-05-04

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