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The concentration of the alpha subunit of human FSH (h-FSH) was measured in serum throughout normal menstrual cycles and when LH-RH was administered on the first and second days of menstruation. In moral cycles, the alpha h-FSH subunit was shown to circulate in the free form, with the highest concentration occurring at the midcycle peak of LH and FSH. The concentration of the alpha h-FSH subunit during the follicular phase was not significantly different from that observed during the cycle's luteal phase.


The response to the administration of different concentrations of LH-RH (10ug and 100ug) is an increase in circulating levels of alpha h-FSH subunit directly related to the increases in LH and FSH.

Jaime Saavedra, Profesor Auxiliar, Departamento de Obstetricia y Ginecología, Facultad de Salud, Universidad del Valle, Cali, Colombia

Profesor Auxilia, Departamento de Obstetricia y Ginecología, Facultad de Salud, Universidad del Valle, Cali, Colombia

Keith Mashiter, Endocrinologist, Senior Lecturer in Medicine and Chemical Pathology Royal Postgraduate Medical School Hammersmith Hospital, London, U. K.

Endocrinologist, Senior Lecturer in Medicine and Chemical Pathology Royal Postgraduate Medical School Hammersmith Hospital, London, U. K.

Jaime Saavedra, & Keith Mashiter. (1986). Circulating levels of FSH-h alpha subunit, FSH and LH in peripheral blood during the menstrual cycle and after stimulation with synthetic gonadotropin hormone (LH-RH). Colombia Medica, 17(1), 22–26. https://doi.org/10.25100/cm.v17i1.6072

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