Main Article Content



Introduction: Although the association of infection by toxoplasmosis with the development of nephrotic syndrome is

uncommon, cases of this association have nevertheless been reported in the literature for more than two decades, not only

for congenital toxoplasmosis, but also in acquired cases, and occasionally in immunocompetent patients.

Development: A case is presented of an immunocompetent patient aged 15 with clinical and laboratory indications of

nephrotic/nephritic syndrome, in whom serological tests showed toxoplasma infection.

Conclusion: The presentation of nephrotic syndrome in ages where it is not commonly seen, leads to clinical suspicion of

secondary causes. Active search for possible causes should include

common tropical infections.


Tania González Velásquez, residente

The authors state that no financial support or author involvement with organizations with financial interest in the subject matter exists, and that no actual or potential conflict of interest exists.

González Velásquez, T., Barrios, E. J., & Duran Botello, C. D. B. (2012). Nephrotic syndrome with a nephritic component associated with toxoplasmosis in an immunocompetent young man. Colombia Medica, 43(3), 226–229.

Baum M. Pediatric glomerular diseases. Curr Opin Pediatr.


Alpers C. The Kidney. In: Kumar V, Abbas AK, Fausto N, Aster J,

eds. Robbins & Cotran Pathologic Basis of Disease. 7 ed. Saunders

Elsevier; 2012:982-3.

Gipson DS, Massengill SF, Yao L, Nagaraj S, Smoyer WE, Mahan

JD, et al. Management of Childhood Onset Nephrotic Syndrome.

Pediatrics. 2009;124(2):747-57.

Roth KS, Amaker BH, Chan JC. Nephrotic syndrome: pathogenesis

and management. Pediatr Rev. 2002;23(7):237-48.

van Velthuysen ML, Florquin S. Glomerulopathy associated

with parasitic infections. Clin Microbiol Rev. 2000;13(1):55-66,

table of contents.

Huldt G. Studies on experimental toxoplasmosis. Ann N Y Acad

Sci. 1971;177:146-55.

Shahin B, Papadopoulou ZL, Jenis EH. Congenital nephrotic

syndrome associated with congenital toxoplasmosis. J Pediatr.


Hill D, Dubey JP. Toxoplasma gondii: transmission, diagnosis

and prevention. Clin Microbiol Infect. 2002:634-40.

Montoya J BJ, Kovacs J. Toxoplasma gondii. In: Mandell GL,

Bennett JE, Dolin R, eds. Mandell, Douglas, and Bennett’s principles

and practice of infectious diseases. 7 ed. Elsevier; 2010:1112-

De Salvador-Guillouet F, Ajzenberg D, Chaillou-Opitz S, Saint-

Paul MC, Dunais B, Dellamonica P, et al. Severe pneumonia during

primary infection with an atypical strain of Toxoplasma gondii

in an immunocompetent young man. J Infect. 2006:e47-50.

Carme B, Bissuel F, Ajzenberg D, Bouyne R, Aznar C, Demar M,

et al. Severe acquired toxoplasmosis in immunocompetent adult

patients in French Guiana. J Clin Microbiol. 2002;40(11):4037-44.


Download data is not yet available.
Received 2011-06-15
Accepted 2011-10-11
Published 2012-09-28