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Introduction: The Kaposi’s sarcoma (KS) incidence has markedly changed in the general population since the onset of the AIDS epidemic in the eighties and after the introduction of the Highly Active Antiretroviral Therapy (HAART) in the nine­ties.

Objective: To investigate incidence rate trends for Kaposi’s sarcoma before and during the (HIV/AIDS) epidemic in Cali, Colombia.

Methods: Exploratory ecological study that included all Kaposi’s sarcoma cases identified by the Cali Cancer Registry from 1962-2007, and 12,887 cases of HIV/AIDS recorded in the Municipal Health Secretariat of Cali between 1986 and 2010. The joinpoint regression model was used to conduct the incidence rate analyses between the years 1962 and 2010.

Results: A total of 349 KS cases were identified during the study period. Only 5.3% of the cases (n=20) were diagnosed in the pre-epidemic era (1963-1987), of these, 35.0% were women, and 90.0% of the tumors were located on the skin. In contrast, 94.7% of KS cases (n=329) were discovered after the emergence of HIV-AIDS. There was a significant decrease in the proportion of women (10.9%, p <0.001) and an increase in the frequency of tumors with an extra-cutaneous location (19.1%, p <0.01) com­pared to those cases diagnosed in the pre-epidemic era. Notification rates of HIV/AIDS have decreased since 2002 in both genders but KS incidence rates have decreased since 2004 in men only.

Conclusion: The downward trend in the incidence of these diseases may be associated with factors that prevent the trans­mission of HIV infection or limit the spread of HIV in the community. Cancer registries represent a resource for timely, population-based surveil-lance of HIV-associated malignancies in Cali, Colombia.

Oscar Londoño

Secretaría de salud publica municipal de Cali

Luz Stella García, Universidad del Valle

Registro Poblacional de Cancer de Cali - Universidad del Valle

Paola Collazos, Universidad del Valle

Registro Poblacional de Cancer de Cali -Universidad del Valle -

Luis Eduardo Bravo

Registro Poblacional de Cancer de Cali - Universidad del Valle
Saldarriaga-Cantillo, A., Londoño, O., García, L. S., Collazos, P., & Bravo, L. E. (2012). Epidemiological surveillance of the HIV/AIDS complex through the analysis of trends in the incidence of Kaposi’s sarcoma in Cali, Colombia. Colombia Medica, 43(4), 273–280. https://doi.org/10.25100/cm.v43i4.1211

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Received 2012-09-14
Accepted 2012-12-12
Published 2012-12-13

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