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Drug repositioning is a strategy that identifies new uses of approved drugs, to treat conditions different from their original purpose. With the advance of COVID-19 and the declaration of a pandemic; It has become the closest alternative to slow the advance of the virus. Antimalarial, antiviral drugs, antibiotics, glucocorticoids, monoclonal antibodies, among others, are being studied; his findings, although preliminary, could establish a starting point in the search for a solution.

In this article, we present a selection of drugs, of different classes and with potential activity to combat COVID-19, whose trials are ongoing; and as proofs of concept, double blind, event-driven add-on, would allow proposing research that generates results in less time and preserving the quality criteria for drug development and approval by regulatory agencies.

Vicente Benavides-Cordoba, Universidad del Valle. Cali, Colombia


Physiotherapist / Universidad del Cauca
Specialist in Cardiopulmonary Physical Therapy / Universidad del Valle
PhD (c) in Biomedical Sciences / Universidad del Valle
Clinical Training Fellowship / European Respiratory Society - Amsterdam Medical Center

Research Area
Pulmonary Rehabilitation, Pulmonary Hypertension, Drug Repositioning.


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Benavides-Cordoba, V. (2024). Drug Repositioning for COVID-19. Colombia Medica, 51(2), e–4279.


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Received 2020-04-09
Accepted 2020-04-19
Published 2024-05-16